Cancer 2 Flashcards
Describe The route to cancer, The pathway of development of colo-rectal Cancer and 6 points for comparison between Oncogenes and tumour suppressor genes
pg 9
Explain what happens in an example of inherited Cancer
pg 5
List two functions of Tumour Suppressor Genes and state overall function
pg 6
Explain an Example of Chromosomal Translocation in Cancer
p3
Why are Proto-oncogenes important in cancer
pg 2
Give the details of the Signal Transduction Pathways in cancer following oncogene activation, with a description of the position of essential proteins. Include the example of RAS protooncogene protein in you answer.
State Function location, associated human cancers of
of 6 different Tumour Suppressor Genes
p 6, look directly at table last time before exam
State Function, mechanism of action, location and associated human cancers of 5 human cancers(look directly at table)
pg 4 ,look directly at table
Explain SIgnficance of p53 in cancer
pg 6
Explain different methods for Oncogene Activation
p2
Give 6 The Hallmarks of Cancer
p1
Why are TSGs important in cancer, why were they discovered before protooncogenes
Illustrate a problem that can take place with an APC Tumour Suppressor Gene
pg 7
Describe The Cell Cycle and its relation to life, death and cancer
p1
