calcium and phosphorous metabolism

Question 1

composition of bone

Answer 1

matrix and cells

Question 2

inorganic component of bone

Answer 2

Calcium & hydroxyapatite

Question 3

cells of the bone

Answer 3

osteoclast, osteoblast, osteocyte

Question 4

osteoblasts synthesize

Answer 4

type I collagen

Question 5

osteoclasts dissolutes

Answer 5

hydroxyapatite

Question 6

biological roles of phosphate

Answer 6

mineralized tissue

phosphorylated metabolites

Question 7

how many percent is calcium in mineralized tissue

Answer 7

99%

Question 8

percent phosphate in mineralized tissue

Answer 8

80%

Question 9

how to maintain Ca balance

Answer 9

net intestinal absorption must be exactly balanced by urinary excretion

Question 10

this type of balance is seen in growing children

Answer 10

Positive Ca Balance

Question 11

Calcium balance wherein the Ca absorption is greater than urinary excretion

Answer 11

Positive Ca Balance

Question 12

This type of balance is seen in women during pregnancy or lactation

Answer 12

negative Ca balance

Question 13

calcium balance wherein intestinal Ca absorption is less than urinary excretion

Answer 13

negative Ca balance

Question 14

84 amino acids polypeptide hormone

Answer 14

PTH

Question 15

what mediates the release of of PTH and thru what

Answer 15

A decrease in plasma cells thru Ca Sensing Receptor

Question 16

decrease in serum Ca _____ PTH secretion

Answer 16

increases

Question 17

severe decrease in serum (mg) _______ PTH secretion

Answer 17

inhibit (hypoparathyroidism)

Question 18

32 amino acid peptide

Answer 18

calcitonin

Question 19

Major action of calcitonin

Answer 19

inhibit bone resorption

Question 20

where is the calcitonin released from

Answer 20

parafollicular cells

Question 21

what can stimulate calcitonin release

Answer 21

increased plasma calcium