caffeine

Question 1

Methyxanthines

Answer 1

Theophylline

Theobromine

Question 2

Sources of Caffeine

Answer 2

Coffee
Tea
Chocolate
Soda
Drug preperations

Question 3

sources of Theophylline

Answer 3

Tea

Question 4

Sources of Theobromine

Answer 4

Chocolate

Question 5

Caffeine content in various sources

Answer 5

Coffee (5 oz)      
100 mg
Tea ( 5 oz )       
50 mg
Soda (12 oz)
40 mg
Chocolate (Bar)
10 mg
Medications
variable

Question 6

Mechanisms of Action

Answer 6

Blockade of adenosine receptors (low doses)

inhibition of phosphodiesterase (high doses)

Blockade of GABA A receptors (high doses)

Increased calcium release (Very high doses)

Question 7

Methylxanthines and Adenosine A 2 receptors

Answer 7

at low doses, Methylxanthines block Adenosine A2a receptors

Minor inhibitory transmitter

A2a receptors are blocked by Methylxanthines causing mild disinhibition of the Brain

Question 8

Acute Cognitive and Behavioral effects of caffeine

Answer 8

Arousal
Alertness
Wakefulness
Increased Energy

Increased concentration
Improved Reaction
Increased Dexterity

Question 9

Acute physiological effects of caffeine

Answer 9

• decreased blood flow to brain
• Increased incidence of migraine headaches
• Decreased incidence of migraine headaches
• Increased respiration rate
• Dilated airways
• Increased gastric secretions
• Diureses

Question 10

Caffeine toxic effects

500 - 1000 mg

Answer 10

Anxiety
Irritability
Insomnia
Fever
Flushing

Question 11

Caffeine toxic effects

>1000 mg

Answer 11

Paranoia
Delusions
Hallucinations
Stereotypes

Question 12

Therapeutic uses of Methylxanthines

Answer 12

Headache
Asthma
Narcolepsy
Sleep Apnea

Question 13

Caffeine tolerance

Answer 13

cellular tolerance

Behavioral tolerance

contextual tolerance

Question 14

Caffeine Cellular Tolerance

Answer 14

Increase in Adenosine receptors

Question 15

Caffeine Behavioral Tolerance

Answer 15

Functioning in Presence of Drug

Question 16

Caffeine Contextual Tolerance

Answer 16

Context in which drug is taken

Induces tolerance

Question 17

Caffeine physical dependence

Answer 17

Headache
Fatigue
Craving

Question 18

Caffeine Psychologicl Dependence

Answer 18

Weak Reinforcer

Increases release of dopamine in cortex

Question 19

Caffeine Health Risks?

Answer 19

Cancers
Benign Breast Disease
Reporduction
Cardiovascular
Anxiety Disorders
Caffeinism
Physical Dependence

Question 20

Caffeine Health Risks?

Cancers

Answer 20

no clear association

Question 21

Caffeine Health Risks?

Benign breast Disease

Answer 21

Increases sensitivity

Question 22

Caffeine Health Risks?

Reproduction

Answer 22

Fertility, miscarriage, growth

Question 23

Caffeine Health Risks?

Cardiovascular

Answer 23

tachycardia, arrythmia

Question 24

Caffeine Health Risks?

Anxiety Disorders

Answer 24

Precipitates panic attacks

Question 25

Caffeine Health Risks?

Caffeinism

Answer 25

Agitation, Mood changes

Question 26

Caffeine Health Risks?

physical dependence

Answer 26

withdrawal effects

Question 27

Caffeine use and disease

Answer 27

associated with LOWER risk of diseases

• Diabetes (type 2)
• Cardiovascular
• Liver Disease
• Parkinsons Disease

*Coffee contains anti-oxidants that are anti-inflammatory

Question 28

low to moderate caffeine consumption

Answer 28

recommended

<= 3 cups per day