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Bacteriology & Mycology > C. Pseudotuberculosis > Flashcards

C. Pseudotuberculosis Flashcards

1
Q

what are the characteristics of C. pseudotuberculosis

A

gram +
facultative
intracellular
coccobacillus

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2
Q

what does C. pseudotuberculosis cause

A

chronic abscess infection

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3
Q

what species does C. pseudotuberculosis affect

A

sheep
goats
horses
cattle

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4
Q

in what species does this bacteria cause caseous lymphadenitis

A

sheep & goats

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5
Q

what does C. pseudotuberculosis cause in horses

A

ulcerative lymphangitis

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6
Q

what can ulcerative lymphangitis cause

A

external and internal abscesses

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7
Q

what are the main virulence factors for C. pseudotuberculosis

A
  1. EXOTOXIN - PHOSPHOLIPASE D
  2. facultative intracellular pathogen
  3. surface lipid coat
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8
Q

how does C. pseudotuberculosis enter the body

A
  • skin breaks
  • ingestion
  • inhalation
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9
Q

where does the C. pseudotuberculosis infection start (manifest)

A

lymph nodes

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10
Q

how does Phospholipase D effect the pathogenesis of C. pseudotuberculosis

A

increases vascular permeability and spreads the infection

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11
Q

what is a chronic and contagious disease in sheep and goats caused by C. tuberculosis

A

caseous lymphadenitis

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12
Q

what are the signs of caseous lymphadenitis

A

-abscesses in the skin, lymph nodes and internal organs
-weight loss, poor health
-reduced wool and milk production

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13
Q

what is another name for caseous lymphadenitis in female goats/sheep

A

Thin Ewe Syndrome

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14
Q

in what group of animals are we most concerned about caseous lymphadenitis

A

small ruminant production

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15
Q

what are the 2 forms of caseous lymphadenitis

A

external & internal presentation

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16
Q

what are the common clinical signs of an external case of caseous lymphadenitis

A

Infections of:
- skin
-subcutaneous tissue
-peripheral lymph nodes

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17
Q

what are common clinical signs in a case of internal caseous lymphadenitis

A

Abscesses in:
-lungs
-liver
-kidneys
-spleen
-internal lymph nodes

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18
Q

what is the common characteristic of an early stage caseous lymphadenitis

A

pale green abscess

19
Q

what is the common characteristic of a late stage case of caseous lymphadenitis

A

-hardened cream abscess
-“cheesy” / “onion-like”

20
Q

where can ulcerative lymphangitis be found in a horse/cattle

A

external & internal

21
Q

what are common presenting signs of ulcerative lymphangitis

A
  • inflammation of lymphatic vessels
    -formation of abscesses on legs
    -thick green extrudate
22
Q

True or False:

ulcerative lymphangitis is a localized infection

A

FALSE
ulcerative lymphangitis can spread to other organs due to the involvement of the lymph system

23
Q

True or False:

Internal abscesses are hard to diagnose

A

true

24
Q

what are the common clinical signs associated with internal abscesses of ulcerative lymphadenitis

A

-weight loss
-fever
-depression
-colic

25
Q

where are the internal abscess of ulcerative lymphadenitis often found

A

liver

26
Q

what is the diagnosis used for external abscesses of ulcerative lymphadenitis

A

bacteria culture
- ELISA for antibody detection
-isolation and PCR confirmation

27
Q

what bacteria causes ulcerative lymphadenitis in horses/ cattle

A

C. pseudotuberculosis

28
Q

what is not very effective as a treatment of internal abscesses due to ulcerative lymphadenitis

A

antibiotics - thick abscess capsule and intracellular location

29
Q

how does one treat an external abscess formed by ulcerative lymphadenitis

A

surgical incision to drain

30
Q

what is the prevention protocol for C. pseudotuberculosis

A

vaccination
-inactivated whole cell wall and phospholipase D

31
Q

which corynebacterium bacteria is mostly found in female cattle

A

C. renale

32
Q

where does C. renale infect

A

-bladder
-ureters
-kidney
-pelvis

33
Q

what is the pathogenesis of C. renale

A

attachment to the epithelial cells of the urinary and reproductive tracts and ascends into the kidneys

34
Q

what is the result of C. renale in the kidneys

A

pyelonephritis

35
Q

what other clinical signs/ problems can occur from the presence of C. renale

A
  1. hemorrhagic cystitis
  2. ulceration of the bladder
  3. ureteritis
  4. pyelonephritis
36
Q

what are the clinical signs of C. renale

A

-arched back
-urine in small frequent quantities
-presence of albumin, leukocytes, and small blood clots in urine
-fever
-anorexia

37
Q

what bacteria is normally found in the prepuce of sheep and goats

A

C. pilosum

38
Q

what does C. pilosum cause in goats and sheep

A

posthitis

39
Q

what is posthitis

A

preputial ulcerative dermatitis

40
Q

what bacteria is commonly associated with Posthitis

A

C. pilosum

41
Q

what is a predisposing factor for Posthitis

A

high protein diets
high urea excretion = high ammonia

42
Q

what is a concern with Posthitis

A

secondary bacterial infections

43
Q

what is the treatment of Posthitis

A

penicillin
trimethoprin-sulfamethaxazole

44
Q

what is the prevention protocol for C. pilosum

A

reduction in protein diet

Bacteriology & Mycology (15 decks)

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