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PCOL 2 > C. 47, ANTIMYCOBACTERIAL DRUGS > Flashcards

C. 47, ANTIMYCOBACTERIAL DRUGS Flashcards

1
Q

What are the first line tubercolosis drugs?

A

Isoniazid, ethambutol, rifampin, pyrazinamide

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2
Q

Provide 5 examples of second-line antituberculosis drugs.

A

Amikacin, Clofamazine, Cycloserine, Rifabutin, Streptomycin

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3
Q

what is the moa of isoniazid?

A

inhibit synthesis of mycolic acid

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4
Q

what is the moa of rifampin?

A

inhibits DNA-dependent RNA polymerase, thereby blocking production of RNA.

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5
Q

what is the moa of ethambutol?

A

inhibits mycobacterial arabinosyl transferases

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6
Q

causes drug-induced systemic lupus erythematosus

A

Isoniazid

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7
Q

imparts harmless orange color to urine, sweat, and tears

A

Rifampin

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8
Q

causes retrobulbar neuritis

A

Ethambutol

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9
Q

Provide the 3 drugs used in leprosy

A

Rifampin, Dapsone, Clofazimine

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PCOL 2 (6 decks)

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