Bunyavirus Flashcards

1
Q

Which viruses can undergo reassortment of RNA segments?

A

Bunyaviridae

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2
Q

From where does the Bunyavirus get its envelope?

A

Budding through the Golgi Apparatus

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3
Q

How many serogroups of Bunyavirus are there?

A

10

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4
Q

Which bunyavirus causes encephalitis?

A

California Encephalitis Virus

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5
Q

What is the clinical presentation of California Encephalitis Virus?

A
  1. Abrupt Onset
  2. Bifrontal Headache
  3. Fever, vomiting
  4. Aseptic Meningitis
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6
Q

What is LaCrosse Encephalitis?

A

A type of California Encephalitis Virus

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7
Q

What are the types of Bunyavirus that can cause hemorrhagic fever?

A
  1. Orthobunyavirus (Bunyawera Serogroup)
  2. Phlebovirus
  3. Hantavirus
  4. Arenaviridae
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8
Q

How is Orthobunyavirus transmitted?

A

Ticks

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9
Q

Which viruses cause Crimean Congo Hemorrhagic Fever?

A

Orthobunyavirus (Bunyawera Serogroup)

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10
Q

How is Phlebovirus transmitted?

A

Sand flies

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11
Q

What are the clinical symptoms of Phlebovirus?

A

HA, Fever, myalgia, photophobia, stiff neck, papules (recovery in 2yrs)

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12
Q

Which virus infects sheep and may be transmitted to humans?

A

Rift Valley Fever Virus

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13
Q

What are the symptoms of Ridt Valley Fever Virus?

A

Saddleback fever, GI sx, Joint pain, hemorrhagic fever

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14
Q

What are the two types of Hantavirus?

A
  1. Korean Hemorrhagic Fever Virus

2. Hantavirus Pulmonary Syndrome

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15
Q

Which disorder causes renal failure and may be transmitted by urine/feces of rodents?

A

Korean Hemorrhagic Fever Virus

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16
Q

What is the cause of Hantavirus Pulmonary Syndrome?

A

Aerosols that originate from mouse feces that are burned by Native Americans of the Southwest

17
Q

What is an effective treatment for Hantavirus Pulmonary Syndrome?

A
  1. Ribavirin
18
Q

What are the two groups of Arenavirus?

A
  1. Old World (Lymphocytic Choriomeningitis Virus (LCM) and Lassa Virus)
  2. New World (Tacaribe Virus, Junin and Machupo)
19
Q

Which demographic is susceptible to LCM Virus?

A

Lab workers in close contact with rodents and hamster owners

20
Q

What is the clinical presentation of Lymphocytic Choriomeningitis Virus (LCM)?

A

Mild Influenze like symptoms, possible aseptic meningitis

21
Q

Which virus can cause serious fetal disease in pregnant women?

A

LCM

22
Q

Which virus results in a severe febrile illness involving many organs that causes skin hemorrhages, mouth ulcers and muscle ache?

A

Lassa Virus

23
Q

Where is Lassa Virus usually seen?

A

Africa

24
Q

Where is Tacaribe Complex usually seen?

A

South America

25
Q

What is a hemorrhagic fever?

A

Petechiae, bleeding in GI, uterus, nasal and GU tract with a fever