Bugs Flashcards
protein A
surface protein on Staph that binds Fc of IgG, interferes with opsonization
TSST-1
Staph toxin causing toxic shock syndrome, superantigen
staph enderotoxin
causes food poisosing from preformed staph toxin, from improperly stored food, 4 hours after eating
exfoliative toxin
in staph, causes blisters
SSp-1 and SSP2
fimbriae (pili) on staph epidermidis
AtlE
surface peptidoglycan hydrolase that binds to polystyrene, staph epi
treatment for staph epi
vancomycin, linezolid and daptomycin
types of issues in Strep A infections
- Skin and mucous membrane infections (impetigo)
- deep tissue infetions (nec fas, cellulitis)
- toxigenic (scarlet fever, toxic shock)
- PSGN
- rheumatic fever
M protein
major virulence factor in Group A strep, attachment, resistant to phagocytosis and complement
exotoxins in necrotizing fasciitis
streptolysins, stroptokinase, DNAse B
treatment for GAS
clindamycin and penicillin
strep bovis
50% colon cancer when in blood stream, can cause endocarditis
clinical presentation in strep pneumoniae
Meningitis
Otitis media
Pnemonia
Sinusitis
virulence factor in penumococcus
- IgA protease
- phosphoryl choline
- pneumolysin -
- polysaccharide capsule
pneumolysin
pore forming toxin of pneumococcus that impairs mucociliary clearance and kills neutrophils
drugs used to treat pseudomonas
beta-lactams (piperacillin and ticarcillin) fluoroqunolones and aminoglycosides
currant jelly sputum
klebsiela
two aerobic gram negatives talked about in class
pseudomonas and klebsiella