Brucella, Francisella, Taylorella Flashcards
Brucella Characteristics
Non-motile Coccobacilli Obligate symbiotic and pathogenic Facultative intracellular REPORTABLE
Brucella is spread mainly by
Females
Abortions - fetus, placenta have large amount of bacteria
B. Abortus - Species and Cause
Cattle
Abortions
B. Abortus - Pathogenesis
Mucosa/oral/skin –> lymph nodes –> target organ
B. Abortus - Target Organs
Repro organs - uterus, fetus, udder
Articulations
Tendon sheaths
Synovial bursa
B. Abortus - Virulence Factors
Cell Wall - Smooth colonies - increased virulence
Cell Wall - Rough colonies - less virulent - lacks O-polysaccharide
B. Abortus - Vaccinations
Needed for humoral and cellular immunity
B. Abortus - Diagnosis
ELISA
SAW/SAT
Rose bengal test
B. Suis is resistnat in environment but can’t stand what
Sunlight
B. Suis - Biovars (5)
1 - reservoir in hares 2 - hares 3- pigs (most pathogenic) 4 - reindeer and caribou 5 - mice (less pathogenic)
B. Suis - Symptoms
Abortion, Orchitis, infertility Arthritis Tendovaginitis Bursitis Osteomyelitis
B. Suis - Zoonotic? More or less pathogenic than Abortus?
Yes Zoonotic
More Pathogenic
B. Suis - Acute Infection
Fluctuating body temp
Sweating and chills
Malaise
Joint Pain
B. Suis - Chronic
Localization
Necrosis and pus
B. Suis - Pathogenesis
Skin and mucous membranes