Brucella, Francisella, Taylorella Flashcards
Brucella Characteristics
Non-motile Coccobacilli Obligate symbiotic and pathogenic Facultative intracellular REPORTABLE
Brucella is spread mainly by
Females
Abortions - fetus, placenta have large amount of bacteria
B. Abortus - Species and Cause
Cattle
Abortions
B. Abortus - Pathogenesis
Mucosa/oral/skin –> lymph nodes –> target organ
B. Abortus - Target Organs
Repro organs - uterus, fetus, udder
Articulations
Tendon sheaths
Synovial bursa
B. Abortus - Virulence Factors
Cell Wall - Smooth colonies - increased virulence
Cell Wall - Rough colonies - less virulent - lacks O-polysaccharide
B. Abortus - Vaccinations
Needed for humoral and cellular immunity
B. Abortus - Diagnosis
ELISA
SAW/SAT
Rose bengal test
B. Suis is resistnat in environment but can’t stand what
Sunlight
B. Suis - Biovars (5)
1 - reservoir in hares 2 - hares 3- pigs (most pathogenic) 4 - reindeer and caribou 5 - mice (less pathogenic)
B. Suis - Symptoms
Abortion, Orchitis, infertility Arthritis Tendovaginitis Bursitis Osteomyelitis
B. Suis - Zoonotic? More or less pathogenic than Abortus?
Yes Zoonotic
More Pathogenic
B. Suis - Acute Infection
Fluctuating body temp
Sweating and chills
Malaise
Joint Pain
B. Suis - Chronic
Localization
Necrosis and pus
B. Suis - Pathogenesis
Skin and mucous membranes
B. Melitensis
Similar to Abortus but in sheep and goats
Zoonotic and more pathogenic
B. Canis Characteristics
Does not have O antigen
Obligate parasitic
Zoonotic
B. Canis Symptoms
NO FEVER lymphadenitis Late abortion Vaginal discharge Epididymitis Scrotum dermatitis Atrophia testicularis STD
Francisella Characteristics
Pleomorphic non-motile Obligate aerobic Fast growth REPORTABLE
F. Tularensis - Reservoir
Infected lagomorphs
Rodents
Amoeba
F. Tularensis - Transmission
Ticks, mozzie and flies
contaminated water
ingestion
F. Tularensis - Virulence
Capsule
Endotoxin
F. Tularensis - Pathogenesis
Primary pathogen of lagomorphs and rodents
Almost systemic – multi organ failure
F. Tularensis - Symptoms in animal
Rarely seen
Liver, spleen, lungs
F. Tularensis - Symptoms in People
Ulceroglandular lesions Conjunctivitis Pharyngitis Pneumonia Typhoid
F. Tularensis - Diagnosis
BSL3
Serology
PCR
Taylorella Equingenitalis Characteristics
Non-motile
Coccobacillus
Facultative anaerobic
REPORTABLE
Taylorella Equingenitalis Effect in Males
None
Taylorella Equingenitalis Effect in Females
CEM Acute suppurative Self limiting Temporarily sterile Highly contagious Become asymptomatic carriers
Taylorella Equingenitalis Sampling in Stallion
Preputium
Urethra
Fossa Glandis
Sinus urethralis
Taylorella Equingenitalis Sampling in Mare
Fossa clitoridis
Sinus clitoridis
