Bordetella Flashcards
Bordetella Characteristics
Cocco-bacillus
Slow growth
Obligate symbiotic
B. Bronchiseptica has affinity for
ciliated respiratory epithelium
B. Bronchiseptica - causes what in dogs
Kennel cough
B. Bronchiseptica - causes what in pigs
Atrophic rhinitis
B. Bronchiseptica - Virulence - Adhesins
Filamentous haemagglutinin
OMP
Fimbriae
B. Bronchiseptica - Virulence - Toxins
Haemolysin - neutrophil inhibition Dermonecrotic Osteo toxin Tracheal cytotoxin LPS
B. Bronchiseptica - Pigs - Non-progressive rhinitis
Damage of nasal mucosa
B. Bronchiseptica - Pigs - Pneumonic bordetellosis
Primary infection when less than 1 wk
Coughing, dyspnea
High morbidity and mortality
Lung lesions
B. Bronchiseptica - Pigs - Progressive Atrophic Rhinitis
Damage to osteoblasts
Sniffing, Sneezing, Tears, Blood from nose
B. Bronchiseptica - Pigs - Treatment
Difficult
Antibacterial
Vaccination (sow, piglets)
B. Bronchiseptica - Dogs and Cats - Pathogenesis
Endogenic and exogenic
Adhesion to ciliated epithelium –> NH3 production and toxins –> inflammation
B. Bronchiseptica - Dogs and Cats - Symptoms
Dry cough
Runny nose and eye
Decrease appetite
Lethargic
B. Avium - Turkeys
Coryza - irritation and swelling of the mucous membranes in nose
B. Avium - Epidemiology
Older animals are carriers
Transferred via bedding and drinking water
B. Avium - Symptoms
High morbity, low mortality
Decreased growth
Nose discharge + sneezing
Head shaking