Bronchodilators: Beta 2 adrenergic agonists Flashcards
1
Q
What is a short acting Beta 2 agonist?
A
- drug that enhances B2 receptors
2
Q
What are the main functions of Beta 2 adrenergic receptors?
A
- bronchodilation
- vasodilation of blood to smooth muscle
- gluconeogenesis
3
Q
What is the main effect when administering a SABA to an asthmatic patient?
A
- bronchodilation
4
Q
In addition to bronchodilation, what else can SABA medication be useful for in asthma?
A
- stabilise mast cells, inhibiting inflammation
- enhance mucociliary clearance
- ⬇️ vascular permeability
5
Q
Which SABA drug do we need to know about?
A
- salbutamol (ventolin)
6
Q
Which LABA drug do we need to know about?
A
- salmeterol
7
Q
How quickly do SABA drugs take to work and last for?
A
- 10 minutes
- 3-5 hours lasting
8
Q
What are the 2 most common side effects of SABA?
A
- muscle tremors (B2 receptors)
- tachycardia (B1 receptors)
9
Q
How quickly do LABA drugs take to work and last for?
A
- 30 minutes
- 10-12 hours lasting
10
Q
What is the only way LABA can be administered?
A
- inhaled
11
Q
Is LABA ever prescribed in isolation?
A
- no
12
Q
What should LABA be prescribed with?
A
- inhaled corticosteroids
- LAMA
