Bronchiolitis & Pulmonary TB Flashcards

1
Q

what is bronchiolitis?

A

Acute viral LRTI associated with inflammation of the bronchioles

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2
Q

Which age group is most likely to her bronchiolitis?

A

2-12months

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3
Q

What is the most common virus to cause bronchiolitis?

A

Respiratory syncytial virus (RSV)

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4
Q

what are the clinical features of bronchiolitis

A
Coryza
low grade fever
cough
difficulty breathing
apnoeic episodes?
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5
Q

Which children are most likely to get apnoeic episodes in bronchiolitis?

A

infants

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6
Q

What is coryza?

A

rhinitis, inflammation of the mucus membrane of the nose

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7
Q

What will be found on examination in bronchiolitis?

A
low grade fever
tachypnea
hypoxaemia
inspiratory crackles
expiratory wheeze
palpable liver
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8
Q

Why would an infant with bronchiolitis develop a palpable liver on examination?

A

because there can be hyperinflation of the lunch, the diaphragm pushes down in the liver, making it palpable, but does not increase its size

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9
Q

What investigations can be done on a baby with bronchioloitis?

A

CXR - though usually not indicated if it is clinically apparent that bronchiolitis is the cause

Nasopharyngeal aspirate - to test for pathogen. Only done in children who are kept in hispital

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10
Q

What would be found on a CXR of a baby with bronchiolitis?

A

Non-specific, hyperinflation, patchy infiltration, focal atelectasis

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11
Q

on a CXR what is atelectasis?

A

partial collapse or incomplete infiltration

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12
Q

What are the risk factors for severe bronchiolitis?

A

infants

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13
Q

what are the indications for hospitalisation in an infant with bronchiolitis?

A

risk factors present

sat 60 with recesstion and poor feeding

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14
Q

What is the management of bronchiolitis?

A
oxygen
fluids
apneoa monitoring
isolation
nasal continuous postive pressures
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15
Q

What are the complications of bronchiolitis?

A

otitis media

secondary bacterial infection

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16
Q

What can be done for prevention in infants with significant risk factors to bronchiolitis?

A

Can be given Palivizumab which is a monoclonal antibody to RSV

17
Q

What is the difference between TB infection and TB disease?

A

TB infection there is a primary complex which causes a local rection in the lung perenchyma

TB disease is early hatmatogenous dissemination leading to millary TB meningeal TB and extra pulmonary disease (30%)

18
Q

How do symptoms present in TB disease at different ages?

A

school age - silent usually
Infants - poor feeding, failure to thrive, cough tachypneoa
Adolescent - fever, weight loss, night sweats, productive cough

19
Q

How is TB Diagnosed?

A

Positive tuberculin skin test (mantoux)

CXR changes - hilar lymphadenopathy

Histology or culture for definitive diagnosis, ealry morning gastro aspirate in infants

20
Q

How is a Mantoux test carried out?

A

Injected with tuberculin. Left for 48 hours, area of swelling (induration) measured, >10mm is positive. Area of swelling threshold is reduced in high risk or immunosupressed patients.

21
Q

What is the treatment of TB?

A

Rifampicin
Isoniazid
Pyrazinamide
Ethambutol