Bronchiectasis

Question 1

Localized area of the lung whether extrinsic or intrinsic (Harrison pp 1694)

Answer 1

Focal bronchiectasis

Question 2

Underlying systemic or infectious disease process (Harrison pp 1694)

Answer 2

Diffuse bronchiectasis

Question 3

Congenital cartilage with tracheobronchomegaly (Harrison pp 1695)

Answer 3

1. Mounier-Kuhn Syndrome

2. Williams-Campbell Syndrome

Question 4

Affects non-smoking women > 50 years old

Bronchiectasis resulting infection that is non-tuberculosis (Harrison pp 1694)

Answer 4

Mycobacterium Avium-intracellulare Complex

Question 5

Hypothesis in which susceptibility to infection and poor mucocilliary clearance result in microbial colinization of bronchial tree (Harrison pp 1695)

Answer 5

Vicious Cycle Hypothesis

Question 6

Dilated airways arising from parenchymal distortion as a result of lung fibrosis (Harrison pp 1695)

Answer 6

Traction Bronchiectasis

Question 7

Most common clinical presentation of bronchiectasis (Harrison pp 1695)

Answer 7

Persistence of productive cough with ongoing production of thick phlegm

Question 8

Acute exacerbations of bronchiectasis of is characterized by _______. (Harrison pp 1695)

Answer 8

Changes in the nature of sputum production

Question 9

CT of bronchiectasis is characterized as _______. (Harrison pp 1695)

Answer 9

1. Tram-Tracks or signet ring appearance
2. Airway diameter 1.5X of adjacent vessel
3. Lack of bronchial tapering
4. Bronchial thickening with dilated airway
5. Inspissated secretions

Question 10

True or False

Focal bronchiectasis almost always requires bronchoscopy to exclude airway obstruction (Harrison pp 1695)

Answer 10

True

Question 11

What are the treatments involved for bronchiectasis? (Harrison pp 1696)

Answer 11

1. Acute exacerbations usually have 7-14 days duration of antibiotics
2. Hydration and mucolytic administration aerolization of bronchodilators and hyperosmolar agents
3. Anti-inflammatory agents may be use for ABPN and non-inflammatory agents
4. Resection of focal area of suppuration -Lung surgery

Question 12

Possible suppressive treatments for bronchiectasis (Harrison pp 1696)

Answer 12

Administration of an oral antibiotics
Rotating schedule of oral antibiotics
Macrolide 2-3x/ week 
Inhalation of aerolized antibiotics
Intermittent administration of IV antibiotics

Question 13

Possible suppressive treatments for bronchiectasis (Harrison pp 1696)

Answer 13

Administration of an oral antibiotics
Rotating schedule of oral antibiotics
Macrolide 2-3x/ week 
Inhalation of aerolized antibiotics
Intermittent administration of IV antibiotics