Bronchial Asthma - DRUGS

Question 1

SABA Short Acting Beta-2 Agonists

Answer 1

Salbutamol (Ventolin®)
Terbutaline (Bricanyl®)
Pirbuterol (Maxair®)
Fenoterol

Question 2

LABA Long Acting Beta-2 Agonists w/ slow onset

Answer 2

Bambuterol (Bambec®)

Question 3

It is the only beta-2-agonist administered
orally (without inhalational route)

Answer 3

Bambuterol (Bambec®)

Question 4

LABA Long Acting Beta-2 Agonists w/ rapid onset

Answer 4

Formoterol
Salmeterol (Serevent®)

Question 5

Salmeterol + Fluticasone
Formoterol + Budesonide

Answer 5

(Seretide)
(Symbicort)

Question 6

Beta 2 agonist causes nervousness and
tachycardia, hypokalemic T/F

Answer 6

True

Question 7

Bronchodilators that are reserved for
special situations

Answer 7

Sympathomimetic Agents

Question 8

Examples of Sympathomimetic Agents

Answer 8

Epinephrine
Ephedrine
Isoproterenol

Question 9

Drug with affinity to Alpha-1, Beta-1, Beta-2.

Answer 9

Epinephrine

Question 10

indirect agonist, capable siya to increase the release of
catecholamines from the pre-synapse.

Answer 10

Ephedrine,

Question 11

nonselective beta agonist. Beta-1 and Beta-2.
A potent bronchodilator

Answer 11

Isoproterenol

Question 12

DOC for anaphylaxis

Answer 12

Epinephrine

Question 13

Alternative controller medication
because it possesses narrow therapeutic
index

Answer 13

Methylxanthines

Question 14

Methylxanthines cannot be used for long-term management bc mayroon siyang narrow therapeutic index. T/F

Answer 14

True

Question 15

parent molecule of Methylxanthines

Answer 15

CAFFEINE

Question 16

methylxanthine use for asthma

Answer 16

THEOPHYLLINE

Question 17

bronchodilator it inhibits una. PDE 3
enzyme metabolizes cAMP and 2nd
block adenosine receptor

Answer 17

methylxanthine)

Question 18

a synthetic analog of theophylline
less potent and shorter-acting than
theophylline

Answer 18

Dyphylline

Question 19

Methylxanthine that does NOT
exhibit bronchodilation activity. It is not
used for asthma. used for intermittent
claudication

Answer 19

Pentoxifylline

Question 20

1st line reliever in COPD and alternative in
BA (more useful in COPD than in asthma)

Answer 20

Anticholinergics

Question 21

It is obtained from Datura stramonium or the Datura
metel.

Answer 21

Ipratropium (Atrovent)

Question 22

anticholinergics with a 24-hour duration
of action. It is considered long-acting.

Answer 22

tiotropium

Question 23

This type of anticholinergics are
quaternary ammonium compounds. So
therefore, they are poorly absorbed
orally.

Answer 23

Oxytropium

Question 24

Prophylactic agents for asthma
stabilizes the membrane by increasing inward conduction

Answer 24

Mast cells Stabilizers

Question 25

Mast cells Stabilizers that is poorly absorbed from the
gastrointestinal tract and must be
inhaled as a microfine powder

Answer 25

Cromolyn (Intal®)

Question 26

has a very low bioavailability and is
available only in metered-dose
aerosol form.

Answer 26

Nedocromil (Tilade®)

Question 27

is the least prescribed because of the
requirement of four times daily dosing
and because of occasional liver toxicity.

Answer 27

Zileuton (Zyflo®)

Question 28

inhibits 5-lipoxygenase thereby preventing
leukotriene synthesis

Answer 28

5-LOX inhibitor

Question 29

approved for children as young as 6
years of age. contain aspartame

Answer 29

Montelukast (Singulair®)

Question 30

twice a day dosing (dec. patient
compliance)

Answer 30

Zafirlukast (Accolate®)

Question 31

Montelukast chewable tablet that
contains aspartame.

Answer 31

Phenylketonuria

Question 32

They bind to glucocorticoid
receptors on the cytoplasm of cells.
Inhibits Phospholipase A2

Answer 32

Corticosteroids

Question 33

opposite ng Cushing-like syndrome,

Answer 33

Addison’s Disease.

Question 34

Long acting inhaled steroids (first line controller)

Answer 34

B
B
F
F

Question 35

Systematic oral med (short acting)

Answer 35

P/P

Question 36

Systemic parenteral (for status asthmaticus

Answer 36

H
M

Question 37

Example of Anti-Ige Monoclonal Antibodies

Answer 37

Omalizumab,