Breeding And Disease Exam Flashcards
Non-infectious diseases
- Physical, incl. traumatic
- Metabolic/ nutritional
- Neoplastic
- Genetic
- Toxic
- Immune-mediated
- Iatrogenic
- Age-related
Infectious diseases
- Infectious proteins
- Viruses
- Bacteria
- Fungi
- Protozoa
- Metazoan parasites
An infectious agent can be bad when i has one or more of these properties
- Multiple strains
- High morbidity
- Aerosol-spread
- Insect-spread
- Feed-spread
- More than one domestic species affected
- Circulates in wildlife
- Infects people
- Hardy in environment
- Trans-placental and infects fetuses
- Mutable
- Wind-borne
- Carrier state after clinical recovery
- OIE reportable (trade barrier)
- Subclinical infection
Hardware disease
- Traumatic reticuloperitonitis
- Metal on pastures
- Physical, infectious, iatrogenic
- Surgery to remove wire, antibiotics, magnets
Potomac Horse Fever
- Neorickettsia risticii
- infectious, but non-contagious
- Avoid rivers where disease endemic in previous years, vaccines, specific antibiotics
PEP
Post-exposure prophylaxis
Rabies What might you want to know? Where is that information?
If i get rabies can i be treated successfully?
What types of rabies exist?
Do local rabies strains pose risk to me and my livestock?
What will make me suspect livestock have rabies?
Can I get it from livestock? If so how?
Can I be protected through vaccination?
Who tests for rabies and how much does it cost?
Do vaccines work for wildlife?
What will make me suspect local wildlife have rabies?
Can disease be confirmed before mammals/humans die?
Disease Control
Depends on understanding the driving ecological factors for each disease, and which combination of biosecurity, genetic selection and vaccines makes most economical and biological sense.
Where to find reliable, current information
Human Diseases: CDC website WDH web site and press releasesLocal MCP’s Animal Diseases: State vet/WLSB and press release USDA Peer-reviewed papers Texts Selected web sites Local veterinarians Regional d-laboratory personnel
Sheep Diseases
Perinatal diseases/ FPT
Ewe infertility and abortion
Horses
Perinatal diseases/ FPT
Colic
Neurological Diseases
Exercise-associated
Wildlife
Brucellosis
CWD
Cattle
Calves: perinatal diseases/FPT Cows/Heifers: Infertility and abortion Bulls: reproductive soundness Intoxication Brucellosis
Zoonotic
A disease that can be transmitted from animals to humans
Colic
- Abdominal pain, usually pain from intestines
- Horses unusually prone to impactions and anatomical displacements of gut, relative to other species
- Some infections: salmonellosis; PHF
- Varies from mild-life threatening
Strangles
- Highly contagious
- Fever+ lymph node swelling
- Isolate horses with swollen nodes:
No antibiotics unless a) recognize before abscesses form or b) before horse clearly ill - Monitor other horses (rectal temperature)
- Multiple (typically 3x) PCR tests to establish horse free of infection
- Vaccination choices
- DD. From S. Zooepidemicus
Vibrio
Bacterial
Has a vaccine
Has an antibiotic
Chlamydia
Bacterial
Has a vaccine
Has an antibiotic
Q Fever
Bacterial
Has no vaccine
May have an antibiotic
Rabbit Fever
Bacterial
Has no vaccine
Does have an antibiotic
Toxoplasmosis
Protozoal
No vaccine
No antibiotic (ionophores)
Border Disease
Viral
No vaccine
No antibiotics
FPT
Failure of Passive Transfer
- pneumonia, enteritis (scours), septicemia
- About 15% of beef calves
- Illness in the first 28 days
- Death from birth weaning
Scours at 0-3 weeks
Viral Diarrheas
E. Coli
Cryptosporidiosis
Scours at 3-weaning
PGE
Coccidiosis
Salmonellosis
Purplegut
Scours from weaning to adulthood
Johne’s Disease
Dealing with calf scours
Vaccinate the dam for viral diarrhea
Brisket disease
Polygenic trait
Right-sided heart failure
Altitude relates >7,000 ft
Control: PAP test bulls, cull bulls with high PAP
Brucellosis in cattle
B. Abortus
- Esp. Late term abortion and retained placentas
- Zoonotic
- 1934: about 11.5% all US cattle; 2007: 0.0001% all US herds
- Persistence in GYA elk and bison
Anticipating risk for your livestock
- Anytime animals are concentrated
- Anytime animals highly stressed
- Birth/first 2 weeks of neonatal life
- Weaning
- Buying in or in-contact with other herds
- Communal grazing
- Wildlife
Basic concepts
- Here immunity
- Infectious vs. non-infectious disease
- Contagious
- Infection is not disease
- Disease resistance: innate resistance; immune resistance
- Disease reservoirs
- Clinical vs. Subclinical
Visible to Invisible Disease
10:1 ratio
Active immunity
Vaccination
Passive immunity
Vaccinating dams
Tools to CYA
- What you know
- Adequate nutrition
- Biosecurity/bio containment
- Vaccines
- Antibiotics
- Disinfectants
- Anthelmintics
Biosecurity
Minimizing introduction of pathogens, deleterious genes, or toxins into herd or flock
Quarantine
40 days
Effective: short IP + obvious clinical signs in carriers (acute respiratory disease, acute diarrheal diseases, unthrifty animals)
Ineffective: carrier disease states (=carriers that appear healthy), infectious agents in normal animals
Vaccines
Active immunity long lasting
Immunoglobulin
Passive immunity, short duration, expensive
Anamnestic
Immune system “remembers” exposure to agent in vaccine
Do not assume protection until after…
2 weeks after 2nd shot of initial vaccine
Enrofloxacin
Broad-spectrum fluoroquinolone Bacteriocidal Not viruses, not parasites Single high dose or multiple day S/C administration Don’t exceed 20 ml
Disinfectants
Inactivate harmful infectious agents
Dependent on:
Type of organism (spores vs bacterial vs. viral)
Organic material (dirt, manure, milk, pus)
Appropriate contact time
Sufficient concentration
* LABELED effectiveness against target agent *