Breast Pathology Flashcards
List the different methods of obtaining breast histopathology specimens
Needle core biopsy Fine needle aspiration Vacuum-assisted biopsy Skin biopsy Incisional biopsy of mass
What types of therapeutic excision can be done for breast pathology?
Excisional biopsy of mass
Wide local excision of cancer
Mastectomy
What is gynaecomastia?
Breast development in the male with ductal growth without lobular development
List some causes of gynaecomastia
Exogenous/endogenous hormones
Cannabis
Drugs (furosemide)
Liver disease
Fibrocystic change is non-neoplastic and typically affects women of what ages?
Aged 20-50, majority are 40-50
List the clinical features of fibrocystic change of the breasts
Menstrual disturbance
Smooth, discrete lump
Sudden/cyclical pain
Fibrocystic change of the breasts is associated with late menarche and late menopause. True/False?
False
Early menarche, late menopause
Describe the pathological appearance of fibrocystic change of the breasts
Blue-domed cysts with pale fluid
Thin-walled but may be fibrous
How is fibrocystic change managed?
Reassurance
Excision if necessary/symptomatic
What is a hamartoma?
Circumscribed lesion consisting of normal breast tissue but present in abnormal proportion or distribution
A fibroadenoma is a common benign lesion of the breasts - list some clinical features
Painless
Discrete, mobile mass
Peak incidence in 30’s
Describe the pathological appearance of fibroadenoma of the breasts
Circumscribed
Rubbery
Grey-white colour
Biphasic - consists of epithelium and stroma
How is fibroadenoma of the breasts managed?
Reassurance
Excision if necessary
What is sclerosing adenosis?
Benign, disordered proliferation of acini and stroma that can cause a mass or calcification
Describe the pathological appearance of a radial scar
Stellate architecture
Central puckering