Breast Flashcards
What defines Stage 0 breast cancer?
No evidence of cancer cells or invasion of the basement membrane; includes DCIS.
What are the characteristics of Stage IA breast cancer?
Tumor ≤2 cm, no spread outside the breast, and no lymph nodes involved.
What are the two conditions under Stage IB breast cancer?
Microscopic metastases (>0.2 mm but ≤2 mm) in axillary lymph nodes OR tumor in the breast (≤2 cm) with lymph node involvement.
What is the tumor size range in Stage IIA with no lymph node spread?
Tumor >2 cm but ≤5 cm.
What are the conditions for Stage IIA breast cancer with lymph node spread?
Tumor ≤2 cm with spread to axillary lymph nodes OR tumor >2 cm but ≤5 cm with 1-3 axillary lymph node involvement.
What are the two conditions for Stage IIB breast cancer?
Tumor >2 cm but ≤5 cm with spread to 1-3 axillary lymph nodes OR tumor >5 cm with no lymph node involvement.
What are the characteristics of Stage IIIA breast cancer?
Tumor of any size with metastases in 4-9 axillary or internal mammary lymph nodes OR tumor >5 cm with spread to axillary/internal mammary nodes.
What defines Stage IIIB breast cancer?
Tumor of any size with spread to chest wall and/or skin of the breast; may also involve axillary or internal mammary nodes.
What are the criteria for Stage IIIC breast cancer?
Spread to >10 axillary lymph nodes OR lymph nodes above/below the collarbone (supraclavicular) OR both axillary and internal mammary lymph nodes.
What defines Stage IV breast cancer?
Spread of cancer to other parts of the body such as liver, lung, or bone.
What does TNM staging stand for?
T - Tumor size, N - Node status, M - Metastasis.
Which stages are included under early breast cancer?
Stages IA, IB, and IIA.
What is considered borderline early breast cancer?
Stage IIB if the breast mass is small.
What defines locally advanced breast cancer?
Stages IIIA, IIIB, and IIIC with large tumor size (>5 cm) and/or extensive lymph node involvement or chest wall/skin spread.
What is metastatic breast cancer?
Stage IV where cancer cells are found in distant organs.
What is the maximum tumor size in Stage IA breast cancer?
2 cm.
What is the range of microscopic metastases in Stage IB?
> 0.2 mm but ≤2 mm in axillary lymph nodes.
In Stage IIA, what lymph node involvement is seen if the tumor is ≤2 cm?
Spread to axillary lymph nodes.
What distinguishes Stage IIB from Stage IIA based on tumor size?
Stage IIB has tumors >5 cm or tumors >2 cm with lymph node spread.
How many axillary lymph nodes are typically involved in Stage IIIA breast cancer?
4-9 axillary lymph nodes.
What additional structure may be affected in Stage IIIB breast cancer?
The chest wall and/or skin of the breast.
Which lymph nodes are involved in Stage IIIC apart from axillary nodes?
Supraclavicular and internal mammary nodes.
What stage includes both axillary lymph node and internal mammary node spread?
Stage IIIC.
What does the presence of cancer in distant organs indicate in breast cancer staging?
Stage IV (Metastatic breast cancer).
