Brain Tumors (Exam #3)

Question 1

What population are primary brain neoplasms more common in?

Answer 1

Adolescents/young adults

Question 2

What population are secondary brain neoplasms more common in?

Answer 2

Adults 30+ years

Question 3

What is the most common BENIGN primary neoplasm?

Answer 3

Meningioma

Question 4

What is the most common MALIGNANT primary neoplasm?

Answer 4

Glioma

Question 5

What are the three most common sites from which a secondary brain neoplasm metastasizes from?

Answer 5

• Breast
• Lung
• Melanoma

Question 6

What two sxs are most often seen with brain tumors? What signs are often seen too?

Answer 6

• HA
• Seizures

Also, focal neuro deficits (weakness, paresthesias, speech, vision)

Question 7

If there is increased ICP with a brain tumor, what additional characteristics are seen with the HA (3)?

Answer 7

• Nocturnal
• Worse in AM
• Worse with cough/sneeze/Valsalva

Question 8

What is the dx test of choice for brain tumors?

Answer 8

MRI with contrast of Brain

Question 9

What two components must be done to classify brain tumors?

Answer 9

• Histology

- Molecular testing

Question 10

With molecular testing of brain tumors, what two things are evaluated for?

Answer 10

• IDH mutations

- 1p/19q codeletion

Question 11

What three non-pharm tx are often performed for brain tumors?

Answer 11

• Surgery (awake craniotomy)
• Radiation
• Chemo

Question 12

What two meds are often considered for tx of brain tumors (think general)?

Answer 12

• Steroids to reduce edema/mass effect

- Meds to prevent seizures

Question 13

Primary brain neoplasm are often asxs, but if sxs are present, what two are most commonly seen?

Answer 13

• Anosmia

- Visual defects

Question 14

What is the most common Glioma in adults?

Answer 14

Glioblastoma Multiforme (GBM)

Question 15

What are the three types of Glioma?

Answer 15

• Astrocytoma
• Oligodendroglioma
• Ependymoma

Question 16

What type of primary brain neoplasm is a rare form of Non-Hodgkin Lymphoma?

What population is at increased risk?

Answer 16

Primary CNS Lymphoma

- Increased risk if IC

Question 17

What is an important factor in the dx/tx of Primary CNS Lymphoma?

Answer 17

HOLD steroids prior to biopsy

Question 18

With which primary brain neoplasm must you HOLD steroids prior to biopsy?

Answer 18

Primary CNS Lymphoma

Question 19

What is the recommended tx for Primary CNS Lymphoma?

Answer 19

MTX

Question 20

What is the most common brain neoplasm overall in adults 30+ years?

Answer 20

Secondary brain neoplasm

Question 21

What is the recommended tx for ALL secondary brain neoplasm? When might OP vs. emergent referral be considered (2)?

Answer 21

Refer to neurosurgery

• OP if small or asxs
• Emergent referral if large or sxs