Brain structure, dissection and imaging Flashcards

1
Q

The skull, meninges, blood-brain barrier (BBB) and what else make up the protective structures of the brain?

A

Cerebrospinal fluid (CSF)

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2
Q

Name the 2 types of molecules, controlled by the BBB, which are critical for brain function:

A

Glucose
Oxygen

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3
Q

How many layers make up the meninges?

A

3

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4
Q

Name the 2 protective structures whose goal is to constrain and stop the brain from moving around:

A

The skull
The meninges

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5
Q

The brain requires oxygen and glucose for energy, but must be provided via a 3rd-party as it is toxic for blood to touch the brain. Name the nutrient provider of the brain:

A

Cerebrospinal fluid (CSF)

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6
Q

This controls the exit and entry of molecules between the blood and the brain:

A

The blood-brain barrier (BBB)

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7
Q

Too much CSF can cause the ventricles to expand and put pressure on the brain. This phenomenon is called:

A

Hydrocephalus

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8
Q

Name the biggest disadvantage to administering histology, computed tomography (CT) scans, magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI):

A

They are not measures of function

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9
Q

The study of brain tissue is called:

A

Histology

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10
Q

Computed tomography (CT), magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) gives us an idea of what about the brain?

A

Gross anatomy

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11
Q

Which brain imaging technique provides us the finest detail and resolution?

A

Electron microscopy

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12
Q

Which brain imaging technique cannot be used to track firing action potentials in subcortical sturctures?

A

Fluorescent microscopy

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13
Q

Electron and fluorescent microscopy are characterised by a poor or fine spatial resolution compared to other imaging techniques?

A

Fine

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14
Q

fMRI and PET scans have poor ____ resolution:
(spatial, temporal)

A

Temporal

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15
Q

If I wanted to measure changes in metabolic activity, which two imaging techniques would I find most useful?

A

fMRI
PET scans

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16
Q

Like fluorescent microscopy, this brain imaging technique is limited to the cortex:

A

Near-infrared spectroscopy (NIRS)

17
Q

These 2 brain imaging techniques have high temporal resolution and are able to track synaptic activity:

A

Electroencephalography (EEG)
Magnetoencephalography (MEG)

18
Q

EEGs and MEGs are able to differentiate between cell firing in the brain. True or false?

A

False

(Because of the high level of cell firing and varied cell activity, it is difficult to make any meaningful conclusions from individual cells.)

19
Q

MEGs and EEGs have high temporal resolution, but poor spatial resolution. True or false?

A

True

20
Q

____ manipulation refers to the observed changes in the brain as a result of changes in behaviour:

A

Behavioural

21
Q

____ manipulation refers to the observed changes in behaviour as a result of changes in the brain:

A

Neurological