Brain damage and neuroplasticity Flashcards

1
Q

what are the two types of tumours

A

encapsulated and infiltrated

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2
Q

What is a stroke

A

Cerebrovascular accident, when blood flow to an area is interrupted

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3
Q

What area of the hippocampus is larger in taxi drivers?

A

posterior hippocampus

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4
Q

When are glutamate antagonist effective after a stroke?

A

immediately after?

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5
Q

What is an ecapsulated tumour?

A

Tumour grown within the membrane

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6
Q

What is an infiltrated tumour?

A

Tumour that grows through the surrounding tissue

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7
Q

What percentage of tumours are menigiomas?

A

20%

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8
Q

What is an menigioma

A

Tumour grown between the meniges

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9
Q

what are meniges?

A

Protective covering the brain and spinal cord

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10
Q

what did Paramei and Sable say about infiltrating tumours?

A

typically malignant

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11
Q

What is an infarct?

A

area of dead tissue

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12
Q

What is penumbra?

A

Dysfunctional area of the brain

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13
Q

Post-symtoms of a stroke?

A

aphagia, paralysis, apraxia, agnosia

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14
Q

What is a haemorrhagic stroke?

A

Weakened blood vessel supplying the brain bursts

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15
Q

Risk factors for a stroke?

A

smoking, obesity, hear disease, hypertension, diabetes

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16
Q

what is an ischemic stroke

A

stroke caused by blockage

17
Q

What is an embolism

A

piece of blood clot that enters the blood stream

18
Q

what is a mechanism of ischemic stroke?

A

Glutamate (excitatory neurotransmitter

19
Q

What does the excessive release of glutamate do?

A

concentration of Na+ and Ca2+ which kills other neurons from the post-synaptic neuron

20
Q

What is a closed head injury?

A

Head injury with no puncture

21
Q

What is a contusion?

A

bruising of the brain

22
Q

what is a concussion?

A

mild traumatic brain injury

23
Q

what is chronic traumatic encephalopathy?

A

degenerative brain disease associated with repeated head trauma

24
Q

Short term effects of CTE

A

confusion, nausea, headaches, blurry vision

25
Long term-effects of CTE?
addictions (gambling), poor financial decisions, violence
26
Example of open head injury?
Phineas Gage (1848)
27
What area did Phineas Gage damage
Orbitofrontal cortex
28
What do infections in the brain cause?
encephalitis
29
What is encephalitis?
inflammation of the brain
30
Example of brain bacterial infections?
Menigitis, abscesses, pareisis
31
What is toxic psychosis?
chronic insanity produced by a neurotoxin
32
what are auto-immune diseases caused by?
interaction between genes, environmental factors epigenetic deregulation
33
what is down-syndrome?
trisomy of chromosome 21
34
who did the study with hippocampus and the taxi drivers?
Maguire et al. 2000
35
What does the posterior hippocampus do?
intergrates infromation from the spatial field into memory
36
Who did the study on the facial behaviour in brain damaged patients?
Borod et al (2000)
37
What side of the brain is dominant for expression of facial movement
right
38
which side of the brain gets bucco-facial apraxia?
left
39
buccofacial appraxia
cannot make voluntary movements involving facial movements like winking