Bradyarrhythmias Flashcards
Main causes of bradycardia
Failure of either impulse initiation or impulse conduction
MC causes of pathologic bradycardia
SA node dysfunction
AV conduction block
Only reliable therapy for symptomatic bradycardia
Permanent pacemaking
SA node commonly rises from
Right coronary artery
2nd: Left circumflex artery
Action potentials of SA node
relatively depolarized membrane potential
slow phase 0 upstroke, relatively rapid phase 4 depolarization
-40 to -60 mV
MCC of extrinsic SA node dysfunction
drugs
ANS influences
Usual cause of intrinsic SA node dysfunction
Degenerative
Failure to increase HR with exercise
Chronotropic incompetence
failure to reach 85% of predicted max HR at peak exercise or
failure to achieve Hr >100bpm or
Max HR with exercise <2 SD below than age-matched control population
May distinguish SA node dysfunction from slow heart rates that result from high vagal tone
Intrinsic HR
administering propranolol 0.2 mg/kg and atropine 0.04 mg/kg
N = 117.2 - (0.53 x age) bpm
Invasive tests for SA node dysfunction
SNRT (sinus node recovery time)
SACT (sinoatrial conduction time)
combination with Low IHR is a SENSITIVE AND SPECIFIC indicator of SA node dysfunction
Class I indications for pacemaker imlantation in SA node dysfunction
symptomatic brady or sinus pause
symptomatic brady and unresponsive to long term medical therapy
symptomatic chronotropic incompetence
AF with brady and pauses >5s
Persistent AV block is common
myocardial ischemia
aging and fibrosis
cardiac infiltrative diseases
Most rapid conduction in the heart is observed
Bundle of His and bundle branches
Wide QRS in AV block
Delay in distal conduction system
Narrow QRS in AV block
Delay in AV node proper (or less commonly in the Bundle of His)