Bradyarrhythmias Flashcards
Main causes of bradycardia
Failure of either impulse initiation or impulse conduction
MC causes of pathologic bradycardia
SA node dysfunction
AV conduction block
Only reliable therapy for symptomatic bradycardia
Permanent pacemaking
SA node commonly rises from
Right coronary artery
2nd: Left circumflex artery
Action potentials of SA node
relatively depolarized membrane potential
slow phase 0 upstroke, relatively rapid phase 4 depolarization
-40 to -60 mV
MCC of extrinsic SA node dysfunction
drugs
ANS influences
Usual cause of intrinsic SA node dysfunction
Degenerative
Failure to increase HR with exercise
Chronotropic incompetence
failure to reach 85% of predicted max HR at peak exercise or
failure to achieve Hr >100bpm or
Max HR with exercise <2 SD below than age-matched control population
May distinguish SA node dysfunction from slow heart rates that result from high vagal tone
Intrinsic HR
administering propranolol 0.2 mg/kg and atropine 0.04 mg/kg
N = 117.2 - (0.53 x age) bpm
Invasive tests for SA node dysfunction
SNRT (sinus node recovery time)
SACT (sinoatrial conduction time)
combination with Low IHR is a SENSITIVE AND SPECIFIC indicator of SA node dysfunction
Class I indications for pacemaker imlantation in SA node dysfunction
symptomatic brady or sinus pause
symptomatic brady and unresponsive to long term medical therapy
symptomatic chronotropic incompetence
AF with brady and pauses >5s
Persistent AV block is common
myocardial ischemia
aging and fibrosis
cardiac infiltrative diseases
Most rapid conduction in the heart is observed
Bundle of His and bundle branches
Wide QRS in AV block
Delay in distal conduction system
Narrow QRS in AV block
Delay in AV node proper (or less commonly in the Bundle of His)
Intermittent failure of electrical impulse conduction from atrium to ventricle
2nd degree AV block
Slowing of conduction through AV junction
1st degree AV block
Complete failure of conduction from atrium to ventricle
Complete or third-degree AV block
More likely to proceed to higher grades of AV block
Type II 2nd degree AV block
Class I indications for pacemaker implantation in acquired AV block
3rd degree or high grade AV block at any anatomic level associated with:
symptomatic brady
essential drug therapy causing symptomatic brady
asystole >3s or escape rate <40bpm while awake
post op av block not expected to resolve
cath ablation of AV junction
neuromuscular diseases
2nd degree AV block with symptomatic brady
Type II 2nd degree AV block with wide QRS
Exercise-induced 2nd or 3rd AV block without ischemia
AF with brady and pauses >5s
Class I Indications for pacemakers in AV block with MI
Persistent AV block in the His/Purkinje system with bilateral BBB or 3rd degree AV block within or below rhe His after MI
Infranodal AV block and assoc BBB
Persistent and symptomatic 2nd or 3rd degree AV block
Class I indications for pacemaker in chronic bifascicular and trifascicular block
Intermittent 3rd degree AV block
Type II 2nd degree AV block
Alternating BBB