BPH Flashcards
What is BPH
Proliferation of both stromal and epithelial elements
Clinical presentation
Hesitancy, poor stream, post-micturition dribble, frequency, urgency, incontinence, nocturnia
Sometimes dysuria and haematuria
What can Lower urinary tract symptoms lead to
Acute or chronic retention
How can chronic retention present as
Bladder stones
Chronic renal failure
Incontinence
Urinary tract infections
How to assess Lower urinary tract infections
History and examination DRE Quantification of symptoms severity Flow rate Urinary dipstick Blood tests
Management of BPH for mild symptoms
Reassure
Lifestyle modification
Follow-up
Management for moderate symptoms
Pharmacotherapy
Alpha-blockers (adrenoceptor antagonists)
5-alpha reductase inhibitors
Anticholinergics
Management for severe symptoms
Surgery
Role of alpha blockers
Side effects
Adrenoceptor antagonists
-Relaxes SM
Side effects: postural hypotension and dizziness
-Retrograde ejaculate
Action of 5- alpha reductase inhibitors
Blocks formation of dihydrotestosterone from testosterone. This means less dihydrotestosterone reaches androgen receptor in prostate and it shrinks
Surgery for BPH
TURP (go into urethra and shave away prostate)
-Complications: bleeding, UTI, incontinence and impotence