Box 2 drugs Flashcards
Sufentanil trade name?
Sufenta
Sufentanil classification
Opioid agonist
Should you use Sufentanil with pregnant women?
No, it crosses the placenta and causes depression in the neonate.
Sufentanil Induction dose (if it was used for induction)
1-30mcg/kg IV
Sufentanil infusion maintenance dose?
0.005-0.015mcg/kg/min
Sufentanil Epidural bolus and then infusion dose?
Bolus 25-50mcg and then 10-50mcg/hr
Sufentanil MOA?
Acts on opioid receptors in the CNS and periphery, mimics endogenous ligands by binding to these opioid receptors resulting in the activation of pain-modulating (antinociceptive) system.
What is antinocieceptive?
the action or process of blocking the detection of a painful or injurious stimulus by sensory neurons
Sufentanil onset, peak, duration?
IV onset 1-3 min
peak 5 to 6 min
duration is dose dependent
Sufentanil subarachnoid dose (spinal)
5-10mcg
How much more sufentanil do you give for epidural dose compared to spinal?
5x as much, spinal is 5-10mcg and epidural is 25-50mcg
Ketamine trade name?
Ketalor