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MICROBIOLOGY 2.0 > Bordetella > Flashcards

Bordetella Flashcards

0
Q

This organism has bipolar metachromatic granules

A

B pertussis

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1
Q

Describe bordetella pertussis

A

RENAN

ROD
ENCAPSULATED
NEGATIVE
AEROBIC
NONMOTILE
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2
Q

Give some enriched media for b pertussis

A

Bordet-gengou

Potato-blood-glycerol agar

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3
Q

B pertussis are grown in charcoal containing media

A

True

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4
Q

B parapertusis are oxidase positive and urease positive

A

False. Urease positive. Negative oxidase

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5
Q

B bronchoseptica are both urease and oxidase positive

A

True

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6
Q

This bordetella sp causes subclinical infxn and has a silent copy of the pertussis toxin gene

A

B parapertusis

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7
Q

This sp of bordetella causes infxns in animals

A

B bronchoseptica

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8
Q

The highly infective stage of pertussis

A

Catarrhal stage

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9
Q

Catarrhal has the highest amount of bacterial load

A

Catarrhal

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10
Q

What phase are toxins produced and liberated

A

Produced - catarrhal
Liberated - paroxysmal

IPCPC q
7-10days
1-2
2-4
3-4
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11
Q

This condition prediminates in infants

A

Whoop - convulsions

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12
Q

This predominates in older children and adults

A

Paroxysmal coughing

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13
Q

Fatal complication of pertussis though rare

A

Encephalitis

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14
Q

Blood is invaded with pertusis

A

False

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15
Q

Death usually occurs in the 3rd year of life

16
Q

Cbc manifests leukemoid rxn

17
Q

Serologic testing is diagnostic of pertusis

A

No, antibodies do not increase until 3rd wk of illness. Already in paroxysmal. Abx not effective

18
Q

Vancomycin is given for pertussis

A

False. Erythromycin

19
Q

This toxin causes ischemia leading to tracheal necrosis

A

Dermonecrotic toxin

20
Q

This virulence factor mediates adhesion to ciliated epithelial cells

A

Filamentous hemagglutinin

21
Q

This toxin acts with dermonecrotix toxin in causing tracheal necrosis

A

Tracheal toxin

22
Q

This toxin causes pertussis by inhibiting DNA synthesis inhibiting non ciliated cell differentiation

A

Tracheal toxin

23
Q

Tracheal toxin is a peptidolglyan like molecule

24
Q

This exotoxin cholera like is responsible for paroxysmal coughing

A

Pertussis toxin or pertussigen

Di porke p toxin ay ngkakacause ng pertussis

25
Q

This virulence factor is activated by calmodulin. Increases CAMP, increase h20, increase secretions

A

Adenylate cyclase toxin

26
Q

An oligopeptide

A

Pertussigen

27
Q

Promotes lymphocytosis and increases igE and LPS

A

Pertussigen

MICROBIOLOGY 2.0 (7 decks)

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