BOOK Flashcards
is derived from the method’s original use in the separation of colored compound on a suitable adsorbent.
CHROMATOGRAPHY
is particularly useful as a means of separating and purifying complex and closely related chemical substances which are difficulty, if not impossible, to separate by classical methods based on differences in solubility and volatility.
CHROMATOGRAPHY
The basic principles upon which chromatographic separation depends are:
ADSORPTION
PARTITION
ION EXCHANGE
MOLECULAR EXCLUSION
The drug principles are quantitatively remover from the solution by ____ in a narrow band at the top of the column.
ADSORPTION
brings about the separation of a mixture through a competitive process in which the molecules of the mobile phase compete with analyte molecules for polar adsorption sites on the adsorbent.
ADSORPTION CHROMATOGRAPHY