bones Flashcards
osseous tissue
bone, dense connective tissue
osteoblast
mononucleate cell
from bone marrow to form new bone
immature bone cells
outer and inner surfaces of bone
osteocyte
formation of bone and matric maintenance
act as pressure/stress receptors to regulate bone response
in lacuna
osteoclast
bone-resorbing cell
multinucleated cells
dissolve bone
inorganic composition of bone
enable bone to resist compression
2/3 of weight
makes bone hard and rigid
organic composition of bone
1/3 of weight
contribute to tensile strength of bone
gives bone flexibility and toughness
woven bone
mechanically weak
random fiber orientation
rapidly formed by osteoblasts
found in embryo and in fracture callus during healing
lamellar bone
mechanically strong
replaces woven bone after fracture
forms on existing bone surfaces
parallel fiber alignment
when osteoclasts reabsrorb bone they release …… and osteoblasts ——– it
minerals and osteoblasts absorb the minerals
bone healing steps
fracture hematoma formation
fibrocartilaginous callus formation
bony callus formation
bone remodeling
5 levels on bone microstructure
- cortical and cancellous bone
- osteons with haversian systems
- lamellae
- collagen fiber assemblies of collagen fibrils
- bone mineral crystals, collagen molecules and non-collagenous protiens
material tissue density = papp
ratio of mass to volume of the actual bone tissue (excludes porosity)
apparent density = papp
ratio of the mass of bone tissue to the bulk volume
mineral crystal in bone
hydroxyapatite
cortical / compact bone
cylindrical osteons and concentric lamellae
outer wall of bones
transversely anisotropic
asymmetric strength (compression)
aging reduces ultimate stress and strain
spongy / trabecular
random arrangement of trabeculae
random structure with porosity
interior of bones
resist stress in different directions
non-uniform and isotropic material
wolffs law
Bone remodels in response to the mechanical demands placed on
it; it is laid down where needed and resorbed where not needed
as one ages a reduction in ………… bone and decrease in the ………… of ……… bone
cancellous bone
thickness of cortical
cortical bone is strongest in
longitudinal compression
trabecular bone when loaded then unloaded….
develops permanent residual strains