Bone StrucFunc Flashcards

1
Q

What type of bone is lattice-like and organized along lines of stress?

A

Spongy (trabecular/cancellous) bone

Spongy bone provides strength and resists stress and forces without breaking.

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2
Q

What are the four types of bone cells?

A
  • Osteogenic/osteoprogenitor cells
  • Osteoblasts
  • Osteocytes
  • Osteoclasts

Each type of bone cell has a distinct role in bone structure and function.

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3
Q

What is the primary function of bones?

A
  • Structural function
  • Mobility
  • Support
  • Protection for the body
  • Storehouse for essential minerals

These functions are critical for overall body health and function.

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4
Q

What is the composition of bone matrix?

A

25% water, 25% collagen, 50% crystallized mineral salts (Calcium hydroxyapatite)

This composition gives bone its unique properties of hardness and lightness.

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5
Q

What are the two types of osseous tissue?

A
  • Compact (cortical) bone
  • Spongy (trabecular/cancellous) bone

Compact bone makes up 80% of total bone mass, while spongy bone accounts for 20%.

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6
Q

True or False: Compact bone is less flexible than spongy bone.

A

True

Compact bone is denser and provides structural support.

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7
Q

What is osteopenia and at what age does it typically start?

A

Demineralisation of bone starting at age 40, reducing by 1% per year

Osteopenia is particularly worse in women aged 40-45.

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8
Q

Fill in the blank: Bones are continually _______ through childhood and adolescence.

A

remodelling

This process includes the removal and replacement of bone at the same site.

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9
Q

What lifestyle factor is important for developing and healing bone?

A

Weight bearing activity

Lack of activity can result in loss of bone density.

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10
Q

What are the consequences of low bone density?

A
  • Osteoporosis
  • Osteogenesis imperfecta
  • Paget’s disease of the bone
  • Bone cancer
  • Bone infections

These conditions can significantly impact bone health and function.

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11
Q

What factors affect bone remodelling?

A
  • Age
  • Mechanical stress
  • Genetics
  • Environmental factors
  • Calcium & phosphate levels
  • Hormones

Understanding these factors is crucial for maintaining healthy bones.

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12
Q

What is an osteocyte?

A

Mature bone cell

Osteocytes are essential for maintaining bone tissue.

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13
Q

What is the role of osteoblasts?

A

Build matrix and collagen fibers but cannot divide

Osteoblasts are crucial for bone formation.

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14
Q

What is the structure of an osteon?

A

Concentric rings (lamellae) of calcified matrix surrounding vertically oriented blood vessels

Osteons are the basic structural units of compact bone.

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15
Q

What happens to bones as a person ages?

A

Demineralisation occurs, leading to conditions like osteopenia and osteoporosis

Age-related bone loss is a significant health concern, especially for postmenopausal women.

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16
Q

What nutrients are important for bone growth?

A
  • Calcium
  • Phosphate

These minerals are essential for developing strong bones.