Bone physiology Flashcards
1
Q
Bone is composed of _____ embedded in an organic ____
A
- mineral crystals
- matrix
2
Q
The mineral primarily consists of ____ and _____ in a ratio of ___
A
- calcium
- phosphorus
- 2 : 1
3
Q
The organic matter is composed of _____
A
- collagen + (noncollagenized matrix / proteins)
4
Q
The matrix is populated by mesenchymal cells, which differentiate into:
A
- osteocytes
- osteoblasts
- osteoclasts
5
Q
main function of osteoblasts
A
produce osteoid
6
Q
what is osteoid
A
collagenized protein that mineralizes at the tidemark zone as hydroxyapatite crystals are incorporated
7
Q
what happens to osteoblasts when the matrix becomes mineralized bone
A
become embedded and are transformed into osteocytes
8
Q
The osteocyte is in contact with the osteoblast through the _____
A
cannular system
9
Q
Osteoclasts are ____
A
macrophage-like cells
