Bone Physiology Flashcards
1
Q
What are osteocalcin and osteonectin?
A
they are proteins that help osteoblasts to deposit bone
2
Q
Where can we find chondrocytes in a bone?
A
near epiphysis
3
Q
What are the biological roles of calcium?
A
intracellular signal strengthen bone hold cells together at tight junctions cofactor for blood coagulation neuron/muscle excitation
4
Q
What is the serum calcium concentration we maintain?
A
2.5 mM
5
Q
T/F PTH is a peptide
A
True, hence with short half life of 20 minutes
6
Q
How long does PTH exert its effect on
1) osteoclast
2) kidney
3) intestine
A
1) 1-2 hours
2) minutes
3) days
7
Q
What condition do we end up with lack of PTH?
A
hypocalcemic tetany
