Bone morphologies (ossification) and muscle tissue (Lecture 8) Flashcards
What are the two kinds of ossification?
Intramembranous - bone develops directly from mesenchymal tissue.
Endochondral - bone matric is deposited on a preexisting cartilage matric.
** Primary bone is formed in both cases.
Explain intramembranous ossification
- Flat bones (skull), long and short bones growth in width.
- Condensation of mesenchyme - blastema - primary ossification centre.
- Differentiation of osteoblasts - deposition of osteoid.
- Mineralization of the bone matrix - osteoblasts change into osteocytes.
- Bony trabecules, angiogenesis (blood vessels), bone marrow.
- Osteoclasts - bone resorption and remodeling.
What is this slide?
Intramembranous ossification
What is this slide?
Intramembranous ossification
What is this slide?
Intramembranous ossification
Explain the process of endochondral ossification
- Cartilage model.
- Ossification of the bones of the extremities (long and short bones), base of the skull and vertebra.
- Primary and secondary ossification centers.
- Perichondral phase.
- Formation of the bone collar within the perichondrium.
- Endochondral phase.
- Hypertrophy of chondrocytes, calcification
- Osteogenic bud with chondroclasts (branches and grows towards epiphyses).
- Calcified cartilage/calcified bone complex is formed.
- Calcified cartilage/calcified bone complex is removed by osteoclasts.
- Thickening of subperiostal bone.
- Perichondral phase.
Bone growth
Appositional growth
Growth in length - epiphesial plate
Zones:
- Zone of reserve cartilage
- Proliferative zone
- Zone of hypertrophy
- Zone of calcification
- Zone of ossification
- Zone of resorption
What is this slide?
Endochondral ossification
What is this slide?
Endochondral ossification
AZAN staining
What is this slide?
Endochondral ossification
AZAN staining
What is this slide?
Endochondral ossification
HE staining
What is this scheme of?
Scheme showing the organisation of skeletal muscle
What is this slide?
Skeletal muscle
HE staining
What is this slide?
Skeletal muscle
HE staining
What is this slide?
Skeletal muscle
HE staining
What is this slide?
Skeletal muscle
HH staining
What is this slide?
Myotendinous junction
HE staining
What is this slide?
Vascular supply of the skeletal muscle
What is this slide?
Cardiac muscle
HE staining
What is this slide?
Cardiac muscle
HE staining
What is this slide?
Cardiac muscle
HE staining
What is this slide?
Cardiac muscle
HH
What is this slide?
Smooth muscle
HE staining
What is this slide?
Smooth muscle
HE staining
