Bone Growth and Fracture healing Flashcards

1
Q

Cortical Bone has a

A

Diaphysis

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2
Q

Cancellous bone has a

A

Metaphysis

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3
Q

Cortical bone resists

A

Bending and Torsion

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4
Q

Cortical bone in terms of bio active

A

Less

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5
Q

Cancellous bone resists

A

Compression

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6
Q

Cancellous bone is the site of

A

longitudinal growth from physio

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7
Q

What stage of fracture begins immediately after fracture

A

Inflammation with Haematoma and Fibrin Clot

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8
Q

Which by products of cell death are present in stage 1 inflammation after bone fracture

A

lysosomal enzymes

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9
Q

What are Mesenchymal and Osteoprogenitor Cells and when are they present

A

Transformed endothelial cells from medullary canal and/or periosteum
Osteogenic induction of cells from muscle and soft tissues

Stage 1 Inflammation

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10
Q

In Stage 1 inflammation angiogenesis happens what is the oxygen gradient required

A

low

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11
Q

what can produce angiogenic factors under hypoxic factors

A

macrophages

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12
Q

What is gold standard for bone fractures

A

Autogenous Cancellous Bone Graft

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13
Q

what can cause delayed union in bones

A

smoking
warfarin
nsaids
ciprofloxacin

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14
Q

what is osteoclasts doing in non union

A

excessive

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