Bone Growth and Fracture healing Flashcards
Cortical Bone has a
Diaphysis
Cancellous bone has a
Metaphysis
Cortical bone resists
Bending and Torsion
Cortical bone in terms of bio active
Less
Cancellous bone resists
Compression
Cancellous bone is the site of
longitudinal growth from physio
What stage of fracture begins immediately after fracture
Inflammation with Haematoma and Fibrin Clot
Which by products of cell death are present in stage 1 inflammation after bone fracture
lysosomal enzymes
What are Mesenchymal and Osteoprogenitor Cells and when are they present
Transformed endothelial cells from medullary canal and/or periosteum
Osteogenic induction of cells from muscle and soft tissues
Stage 1 Inflammation
In Stage 1 inflammation angiogenesis happens what is the oxygen gradient required
low
what can produce angiogenic factors under hypoxic factors
macrophages
What is gold standard for bone fractures
Autogenous Cancellous Bone Graft
what can cause delayed union in bones
smoking
warfarin
nsaids
ciprofloxacin
what is osteoclasts doing in non union
excessive