Bone & Bone Marrow Flashcards
Functions of bone
Support, protection, movement, mineral and fat storage, blood cell Production
Types of Bones
Long, short, irregular, flat, sesamoid
Long bone structure
• Diaphysis
• Epiphysis
• Articular cartilage
• Periosteum
• Medullary cavity
• Endosteum
Diaphysis
Main shaft of a long bone
Hollow, cylindrical shape and thick compact bone
Provide strong support without cumbersome weight
Epiphysis
• Both ends of a long bone
• Made of spongy bone
• Bulbous shape
• Provide attachments for muscles and give stability to joints
Articular Cartilage
Layer of hyaline cartilage that covers the articular surface of epiphyses
Function to cushion jolts and blows
Periosteum
- Dense, white fibrous membrane that covers bone
- Contains cells that form and destroy bone
- Attaches tendons to bones and contains blood vessels important in growth and repair
Endosteum
- Thin, fibrous membrane that lines the medullary cavity
Medullary Cavity
- Tube-like, hollow space in the diaphysis of a long bone
- In adults, filled with a connective tissue rich in fat (yellow marrow)
- Contains blood vessels important in growth and repair
What is bone tissue
• Most distinctive form of connective tissue
• Extracellular components are hard and calcified
• Rigidity of bone allows supportive and protective functions
Types of bone tissue
Compact and spongy bone
Hydroxyapatite
Crystals of calcium and phosphate that contribute to bone hardness
Calcification
Hydroxyapatite crystals formation
Types of bone cells
Osteoblasts, osteoclasts and osteocytes
Osteoblasts
Bone forming cells, contain framework for deposition of calcium and phosphate
Osteoclasts
Bone-eroding cells, contain mitochondria and lysosomes
Osteocytes
Mature, non-dividing cells surrounded by matrix
Bone marrow
Type of soft, connective tissue spread over wide area of body. Two types: red and yellow marrow
Red marrow
Functions to produce red blood cells
Yellow marrow
Replaces red marrow as person ages, storage of fat and functions as energy storage.
In adults, bone marrow is found in..
Ribs, humerus, bodies of vertebrae, pelvis (sacrum and coccyx), femur
When can yellow marrow change to red?
During times of decreased blood supply including anaemia, exposure to radiation and certain diseases