Bone and soft tissue tumours Flashcards

1
Q

What is a common location for a sarcoma to spread to Haematogenously?

A

Lungs and fascial planes

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2
Q

Name suspicious signs of soft tissue tumours on examination

A

deep, subcutaneous>5cm, rapidly growing, hard and craggy

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3
Q

commonest primary malignant ‘bone’ tumour in older patient

A

Myeloma

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4
Q

commonest primary malignant bone tumour in younger patient

A

Osteosarcoma

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5
Q

What is a Red flag symptom of a bone tumour

A

Deep ache which is worse at night and at rest, persistent and increasing

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6
Q

What should you look for on examination of the bone mass

A

measurement, location, shape, consistency, mobility, tenderness, temperature, neurovascular deficits

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7
Q

Cardinal Malignant features of bone tumours are…

A

unexplained pain of a deep seated and boring nature worse at night, difficulty weight bearing (loss of function), deep swelling, joint effusion, neurovascular effects, fractures

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8
Q

What is the Ix of choice/ most sensitive for a Osteosarcoma?

A

MRI

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9
Q

On Ix what is found on XR if the tumour is active?

A

clear margins, surrounding rim of reactive bone, cortical expansion

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10
Q

On Ix what is found on XR if the tumour is inactive?

A

unclear margins, cortical destruction, periosteum is reactive, onion skinning pattern

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11
Q

On Ix why is an isotope bone scan used?

A

assessing ossification, cortex integrity, staging primarily for the lungs

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12
Q

On Ix why is CT used?

A

staging for skeletal metastases

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13
Q

What method can differentiate between benign and malignant?

A

tissue diagnosis

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14
Q

16f back pain, isotope bone scan shows uptake at the left proximal humerus

A

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15
Q

32m #distal tibia, developed anterior knee pain which is deteriorating. # slow to heal, develops fixed flexion deformity of his knee

A

/

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16
Q

23m knee pain deteriorating continuoisly therapy not working

A

/

17
Q

Osteosarcomas present with what kind of loss of function

A

limping, reduced joint movement, stiff back (especially in children)

18
Q

Osteosarcomas present with what kind of swelling features?

A

warmth over the swelling, generally near the end of long bone and diffuse in malignancy

19
Q

Effects between the ages of 10-20 and is a very rare form of bone tumor…

A

Ewigs Sarcoma

20
Q

Tx of bone tumours are…

A

Chemo, radiotherapy, surgery

21
Q

what are the most common sites for secondary bone tumours?

A

vertebrae> proximal femur, pelvis, ribs, sternum, skull

22
Q

bone is the 3rd most common site for mets after…

A

lung and liver

23
Q

breast tumours most commonly go to…

A

Bone

24
Q

melanomas most commonly go to…

A

Lung

25
Q

Name the most common primary cancer sites to then metastasize to bone?

A

Lung, breast, prostate, thyroid, gi tract, melanoma.

26
Q

how long will a patient with a pathalogical fracutre survive?

A

50% >6m, 30%>1yr

27
Q

what are the methods of preventing a pathalogical fracture?

A

early chemo, prphylactic internal fixation, bone cement, embolisation,

28
Q

What factors does Mirel’s fracutre scoring system use?

A

Site, Pain, Lesion, Size.