Body Fluid Flashcards

1
Q

What is the proportion of body weight accounted for by water?

A

~60%

High body weight: ~40%
Low body weight: ~80%

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2
Q

How is body water regulated?

A

Hormonal mechanisms, circulatory mechanisms and renal mechanisms

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3
Q

What is water balance?

A

Water intake and water loss are equal to each other

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4
Q

What is intracellular fluid and the extracellular body fluid water composition?

A

Intracellular fluid (inside the cell): ~2/3rds of total body water

Extracellular fluid (outside the cell): ~1/3rd of total body water

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5
Q

ECF is subdivided into TWO major compartments. What are they?

A

Interstitial fluid (fluid between cells) ~80%

Plasma (fluid in circulatory system) ~20%

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6
Q

What’s the total volume of water in intracellular fluid?

A

~27l

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7
Q

What’s the total volume of water in interstitial fluid?

A

~11l

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8
Q

What’s the total volume of water in plasma fluid?

A

3-3.5l

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9
Q

What volume is needed for water intake and where does it come from?

A

Metabolic water: 200ml/per day

Food and drink: 1.5l - 2.5l/ per day

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10
Q

Where do we lose water and what is the approximate volume lost per day?

A

Kidneys: 0.5 - 1.5 l/day

Lungs: 0.3 - 0.4 l/day

Skin & sweat: 0.2 - 1.0 l/day

Faeces: 0.1 - 0.2 l/day

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11
Q

Is the protein content of plasma higher or lower than the interstitial fluid?

A

Higher, because proteins are too large to pass through the pores in the capillary walls.

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12
Q

What happens when plasma osmotic pressure falls?

A

When the plasma volume falls, the fluid will move from the plasma into the interstitial spaces. This can cause oedema.

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13
Q

What causes plasma osmotic pressure to fall?

A

Severe starvation - low protein intake

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14
Q

Where is the cerebrospinal fluid found?

A

In spaces within the brain and the surrounding portions of the brain and spinal cord.

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15
Q

What is the CSF volume?

A

~150ml

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16
Q

What is the role of the CSF?

A

CSF supports and protects the brain and spinal cord and helps supply nutrients.

17
Q

Describe the blood brain barrier?

A

The walls of the brain capillaries are much less permeable (leaky) than capillaries elsewhere in the body, they therefore prevent certain substances from passing
from the CSF to the blood and vice versa.