Body cavity effusions Flashcards
Samples of effusion should be collected in what tube?
EDTA (purple top)
*keep an aliquot in red top if possible
At the time of collection always
Make a slide
Pure transudate parameters
Protein < 2.5 g/dl Nucleated cells < 1000/microl *low numbers -nondegenerate neutrophils -monocytes -lymphocytes -occasional reactive mesothelium
Transudates from hypoabluminemia happen when albumen conc
conc < 1.0 g/dl
*Unless hypertension also present
Conditions resulting in pure transudates
- Dec. protein production
- Increased protein loss
- Relative decrease plasma albumin
- Increased venous pressure (hypertension)
Decreased protein production seen in patients with
- liver failure ie: cirrhosis
- malnutrition
- maldigestion
- malabsorption
Increased protein loss
- PLN
- PLE
- Intestinal parasitism
- Intestinal neoplasia
Relative decrease plasma albumin
Iatrogenic from too much fluids
Increased venous pressure from
- Portal hypertension secondary to
- chronic liver dz
- portal vein hypoplasia
Uroperitoneum
NON SEPTIC EXUDATE
- Transudate like fluid
- very low protein and TNCC
- Neutrophils typically predominate
- Other biochem abn
- elevated serum BUN and creat
- hypoNa, hyperK
Transudate classification in horses
Protein < 2.5 g/dl
Cells < 1,500/microl
*neuts usually predominate
*can be normal
Modified Transudate parameters
Protein 2.5-5.0 g/dl
Cell count 500-5,000/microl
*majority mononuclear cells
*may eventually look like nonseptic exudate
Clinical conditions resulting in modified transudates
- Congestive heart failure (dog)
- Cats with CHF get chylous effusions - Lymphoma, carcinoma, mesothelioma, hemangiosarc
- Hernias
- Obstruction cranial vena cava, caudal vena cava, hepatic vein
- Trauma
Modified transudates in equines
cell count 5,000-10,000 /microl
Normal if protein < 2.5 g/dl
Abnormal if protein > 2.5 g/dl
*neutrophils will predominate
Causes modified transudate in equines
- proximal enteritis
- thromboembolism
- strangulation of vessels