BOC Study Guide (VIROLOGY - CHAPTER REVIEW) Flashcards

1
Q
  1. Which one of the following provides a presumptive identification of a viral infection?

A. cytopathic effect on cell cultures
B. intranuclear inclusions in RBCs
C. cell lysis of sheep red blood cells
D.presence of mononuclear inflammatory cells

A

A. cytopathic effect on cell cultures

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2
Q
  1. The specimen of choice for detection of RSV is:

A. nasopharyngeal aspirate
B. cough plate
C.expectorated sputum
D.throat swab

A

A. nasopharyngeal aspirate

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3
Q
  1. The genus of virus associated with anogenital warts, cervical dysplasia and neoplasia is:

A. herpes simplex virus
B. human papillomavirus
C. cytomegalovirus
D.Coxsackievirus

A

B. human papillomavirus

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4
Q
  1. Encephalitis is most commonly associated with which of the following viruses?

A. Epstein-Barr
B. herpes simplex virus
C. coxsackie B
D. varicella zoster virus

A

B. herpes simplex virus

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5
Q
  1. Colds and other acute respiratory diseases are most often associated with:

A. Epstein-Barr virus
B. Adenovirus
C. coxsackie B
D.Reovirus

A

B. Adenovirus

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6
Q
  1. The Epstein-Barr virus is associated with which of the following?

A. Chickenpox
B. Hodgkin lymphoma
C.Burkitt lymphoma
D.Smallpox

A

C.Burkitt lymphoma

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7
Q
  1. Which of the following agents is the most common cause of pediatric viral gastroenteritis?

A.adenovirus, serotypes 40 and 41
B.Norwalk virus
C.Coronavirus
D.rotavirus

A

D. rotavirus

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8
Q
  1. Hanta or Sin Nombre Virus is a Bunyavirus found in the 4 Corners area of the US (Arizona, New Mexico, Nevada, Colorado). What is the vector?

A. deer mouse
B. Norwegian rat
C.domestic canine
D.Ixodes tick

A

A. deer mouse

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9
Q
  1. Which type of virus causes severe acute respiratory syndrome?

A. paramyxovIrus
B. Enterovirus
C.Rhinovirus
D. coronavirus

A

D. coronavirus

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10
Q
  1. Which of the following organisms is the causative agent of hand, foot and mouth disease?

A. Adenovirus
B. coxsackie A
C. coxsackie B
D.human herpes virus 6

A

B. coxsackie A

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11
Q
  1. What is the animal reservoir of West Nile Virus?

A. Mice
B. Rats
C. domestic cats
D. birds

A

D. birds

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12
Q
  1. Which one of the following viruses is responsible for the most common congenital infection in the United States?

A. VZV
B. CMV
C.EBV
D.adenovirus

A

B. CMV

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13
Q
  1. Which one of the following clinical syndromes is associated with VZV infection?

A. infectious mononucleosis
B. Shingles
C.primary CNS lymphoma
D.Burkitt lymphoma

A

B. Shingles

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14
Q
  1. Which of the following clinical presentations is associated with HHV8?

A. Kaposi sarcoma
B. Duncan disease
C.fifth disease
D.exanthem infectiosum

A

A. Kaposi sarcoma

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15
Q
  1. In a person vaccinated against hepatitis B virus several years prior, which serological marker would be expected?

A. HBsAg
B. HBeAg
C.anti-HBs
D.anti-HBc

A

C.anti-HBs

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16
Q
  1. The persistence of which marker is the best evidence of chronic HBV infection?

A. HBeAg
B. HBsAg
C.anti-HBe
D.anti-HBs

A

B. HBsAg

17
Q
  1. Which of the following statements regarding antigenic shift or drift in influenza is correct?

A. antigenic drift is due to point mutations in the H&N genes
B. antigenic drift is responsible for pandemics of influenza
C. antigenic shift is responsible for seasonal epidemics of influenza
D. local annual outbreaks of influenza are often due to antigenic shift

A

A. antigenic drift is due to point mutations in the H&N genes

18
Q
  1. This virus is responsible for nearly all cases of infantile respiratory bronchiolitis:

A. parainfluenza virus
B. metapneumovirus
C. coxsackie A virus
D. respiratory syncytial virus

A

D. respiratory syncytial virus

19
Q
  1. Which test is the primary screening test for HIV?

A. serum enzyme linked immunosorbent assay
B. western blot
C. quantitative HIV RNA
D.CD4 count

A

A. serum enzyme linked immunosorbent assay

20
Q
  1. Which of the following HIV tests is the assay for determining response to anti-retrovirals?

A. serum ELISA
B. quantitative HIV RNA
C.CD4 count
D.p24 antigen detection

A

B. quantitative HIV RNA

21
Q
  1. Which one of the following is a characteristic of hepatitis B virus?

A. hepatitis B infects CD4+T lymphocytes.
B. it can be reactivated, causing “shingles”.
C. It is an enveloped DNA virus that is primarily a blood-borne pathogen.
D. This RNA virus is almost always transmitted by the fecal-oral route.

A

C. It is an enveloped DNA virus that is primarily a blood-borne pathogen.