Blood Transfusion Scenarios

Question 1

Patient with blood type A receives blood from blood type A. What happens?

Answer 1

No immune reaction. Both donor and recipient have A antigens on red blood cells, and the recipient’s anti-B antibodies have nothing to target. Safe transfusion.

Question 2

Patient with blood type A receives blood from blood type B. What happens?

Answer 2

Hemolytic reaction. The patient’s anti-B antibodies will attack the B antigens on donor red blood cells, leading to their destruction. Unsafe transfusion.

Question 3

Patient with blood type A receives blood from blood type AB. What happens?

Answer 3

Hemolytic reaction. The patient’s anti-B antibodies will attack the B antigens on the AB donor red blood cells, triggering an immune response. Unsafe transfusion.

Question 4

Patient with blood type A receives blood from blood type O. What happens?

Answer 4

Safe transfusion. Blood type O has no A or B antigens on red blood cells, so there’s nothing for the recipient’s anti-B antibodies to react to. No immune response.

Question 5

Patient with blood type B receives blood from blood type B. What happens?

Answer 5

No immune reaction. Both donor and recipient have B antigens, and the recipient’s anti-A antibodies have no A antigens to target. Safe transfusion.

Question 6

Patient with blood type B receives blood from blood type A. What happens?

Answer 6

Hemolytic reaction. The patient’s anti-A antibodies will attack the A antigens on donor red blood cells, leading to cell destruction. Unsafe transfusion.

Question 7

Patient with blood type B receives blood from blood type AB. What happens?

Answer 7

Hemolytic reaction. The patient’s anti-A antibodies will attack the A antigens on the AB donor red blood cells. Unsafe transfusion.

Question 8

Patient with blood type B receives blood from blood type O. What happens?

Answer 8

Safe transfusion. Blood type O has no A or B antigens on red blood cells, so there’s no target for the recipient’s anti-A antibodies. No immune response.

Question 9

Patient with blood type AB receives blood from blood type A. What happens?

Answer 9

No immune reaction. The patient has no anti-A or anti-B antibodies, so the A antigens on donor red blood cells are not attacked. Safe transfusion.

Question 10

Patient with blood type AB receives blood from blood type B. What happens?

Answer 10

No immune reaction. The patient has no anti-A or anti-B antibodies, so the B antigens on donor red blood cells are not attacked. Safe transfusion.

Question 11

Patient with blood type AB receives blood from blood type AB. What happens?

Answer 11

No immune reaction. Both donor and recipient have A and B antigens on red blood cells, and the patient has no antibodies to attack either antigen. Safe transfusion.

Question 12

Patient with blood type AB receives blood from blood type O. What happens?

Answer 12

Safe transfusion. Blood type O has no A or B antigens on red blood cells, so there’s nothing for the recipient’s immune system to target. No immune response.

Question 13

Patient with blood type O receives blood from blood type A. What happens?

Answer 13

Hemolytic reaction. The patient’s anti-A antibodies will attack the A antigens on donor red blood cells. Unsafe transfusion.

Question 14

Patient with blood type O receives blood from blood type B. What happens?

Answer 14

Hemolytic reaction. The patient’s anti-B antibodies will attack the B antigens on donor red blood cells. Unsafe transfusion.

Question 15

Patient with blood type O receives blood from blood type AB. What happens?

Answer 15

Hemolytic reaction. The patient’s anti-A and anti-B antibodies will attack both the A and B antigens on donor red blood cells. Unsafe transfusion.

Question 16

Patient with blood type O receives blood from blood type O. What happens?

Answer 16

No immune reaction. Both donor and recipient have no A or B antigens on red blood cells, so the recipient’s anti-A and anti-B antibodies have no target. Safe transfusion.