Blood Products And Transfusion Practice Flashcards

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1
Q

What is anaemia?

A

Deficiency in primary signalling mechanisms
Bone marrow defect
Deficiency in the building blocks
Red cells defect, excessive destruction or shortened life span

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2
Q

How long is the life span of red blood cells?

A

35 days

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3
Q

How long do you have between blood being delivered on to the ward and starting a transfusion?

A

30 mins

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4
Q

How long does it take to transfuse a unit of blood?

A

4 hrs

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5
Q

What is the most compatible blood transfusion donor?

A

O

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6
Q

What is the most common donor for fresh frozen plasma?

A

AB

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7
Q

What are the blood products used and their ABO and rhesus matching?

A

Red cells = ABO, Rh and kell negative (female)
Platelets = ABO, Rh
Fresh frozen plasma = ABO
Granulocytes = ABO, Rh, HLA

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8
Q

What do you check when checking a pt for a blood transfusion?

A

Bedside independent checks
Wristband, pt confirmation, component label, component, transfusion prescription
Sign and document

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9
Q

What are the acute immune mediated adverse effects of a blood transfusion?

A
Acute haemolysis
Anaphylaxis
Transfusion associated lung injury
Febrile non-haemolytic
Urticaria
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10
Q

What are the acute non immune mediated adverse effects to a blood transfusion?

A

Bacterial contamination
Circulatory overload
Citrate toxicity

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11
Q

What are the delayed immune mediated adverse effects of a blood transfusion?

A

Delayed haemolysis
Transfusion associated GVHD
Post transfusion purpura

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12
Q

What are the delayed non immune mediated adverse effects of a blood transfusion?

A

Iron overload

Disease transmission

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13
Q

What is the normal platelet count?

A

125-400 x 10 to the power 9

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14
Q

When would irradiated blood products be used?

A

Hodgkin’s lymphoma
Some cytotoxic chemotherapy
Some treatments that impair the immune system
Stem cell transplant setting

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15
Q

When would CMV negative blood products be used?

A

Pregnant women

Fetal and neonate transfusions

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16
Q

Why are red blood cells transfused?

A

To enhance the oxygen carrying capacity of the blood