Blood & Nutrition Flashcards

1
Q

what are the symptoms of iron deficiency?

A

tiredness, pallor, SOB, palpitations

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2
Q

what is the patient counselling for taking iron preparations?

A

take with or after food
take with a glass of orange juice (Vit C aids absorption)

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3
Q

how long should you treat iron deficiency?

A

continue for 3 months after bloods in range

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4
Q

what is the MHRA alert for IV iron?

A

hypersensitivity

monitor for 30 mins every administration

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5
Q

what are the symptoms of megaloblastic anaemia?

A

high MCV
numbness, tingling hands/ feet, muscles weakness, depression

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6
Q

what are the causes of megaloblastic anaemia?

A

Vitamin B12 or folate deficiency or BOTH

  • if both, important to treat B12 first as folic acid alone can mask symptoms and cause neuropathy
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7
Q

how can you treat megaloblastic anaemia?

A

B12:
hydroxocobalamin (IM injection 3 monthly)
cobalamin (oral OD)

Folate:
folic acid 5mg daily for four months

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8
Q

what is the treatment for iron overload?

A

desferrioxamine

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9
Q

what is the treatment for neutropenia?

A

filgrastim

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10
Q

which drugs should be avoided in people with G6PD deficiency?

A

quinolones, nitrofurantoin, aspirin, chloroquine, quinine, sullphonylureas

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11
Q

what is the normal range for potassium?

A

3.5-5.3

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12
Q

what are the symptoms of hypokalaemia?

A

muscle cramps, fatigue, palpitations, arrhythmias

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13
Q

what are the symptoms of hyperkalaemia?

A

fatigue, numbness, SOB, chest pain, palpitations

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14
Q

what drugs cause hypokalaemia?

A

Aminophylline/ theophylline
Beta agonists
Corticosteroids
Diuretics (loop/ thiazide)
Erythromycin/ clarithromycin
Insulin

ABCDEI

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15
Q

what is the treatment of hypokalaemia?

A

mild/ moderate:
oral sando-k

severe:
IV KCl

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16
Q

what drugs cause hyperkalaemia?

A

Trimethoprim
Heparins
ACE/ ARB
NSAIDs
K
Sparing diuretics
Beta blockers

THANKS B

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17
Q

what is the treatment for hyperkalaemia?

A

mild/moderate:
calcium resonium

severe (>6.5):
IV CaCl
soluble insulin
salbutamol

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18
Q

what is the normal range of sodium?

A

133-146

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19
Q

what are the symptoms of hyponatraemia?

A

nausea, headache, confusion, fatigue, irritability, seizures

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20
Q

what are the symptoms of hypernatraemia?

A

thirst, fatigue

21
Q

what drugs cause hyponatraemia?

A

Carbamazepine
Diuretics
Desmopressin
SSRIs

Certain Drugs Ditch Salt

22
Q

what is the treatment of hyponatraemia?

A

mild/ moderate:
oral sodium bicarbonate

severe:
IV NaCl

23
Q

what drugs cause hypernatraemia?

A

Sodium bicarbonate
Corticosteroids
Effervescent forms
Oestrogens/ androgens

Salty CEO

24
Q

what is the normal range of calcium?

25
what are the symptoms of hypocalcaemia?
muscle cramps, confusion, depression, forgetfulness
26
what are the symptoms of hypercalcaemia?
nausea, lethargy, confusion, muscle cramps, arrhythmias
27
how do you treat hypocalcaemia?
calcium supplements if dietary not adequate oral supplements with vit D severe acute/ hypocalcaemic tetany: slow IV calcium gluconate 10%
28
how do you treat hypercalcaemia?
severe: correct dehydration - IV NaCl bisphosphonates + pamidronate corticosteroids calcitonin
29
how do you treat hypercalciuria?
increase fluid intake bendroflumethiazide
30
what is the normal range for magnesium?
0.6-1
31
what are the symptoms of hypermagnesaemia?
muscle weakness, arrhythmia
32
how do you treat hypermagnesaemia?
calcium gluconate
33
how do you treat hypomagnesaemia?
symptomatic: IV/ IM magnesium sulfate mild: oral magnesium
34
what is the normal range of phosphate?
0.87-1.45
35
how do you treat hypophosphotaemia?
oral phosphate supplements
36
how do you treat hyperphosphotaemia?
1st calcium acetate 2nd sevelamer 3rd CaCO3 OR sucroferric oxyhydroxide
37
what are the symptoms of hyperparathyroidism?
thirst, polyuria, constipation, fatigue, memory impaired, CVD, kidney stones, osteoporosis
38
how do you treat hyperparathyroidism?
1st parathyroidectomy drug treatment: cinacalcet supplement vit D if needed bisphosphonate
39
how do you treat an acute crisis of acute porphyria?
IV haem arginate
40
what are the fat soluble vitamins?
A,D,E,K
41
what can a lack of vitamin D cause?
rickets (bow legged)
42
what can a lack of vitamin A cause?
occular defects
43
what can a lack of vitamin E cause?
neuromuscular abnormalaties
44
what are the water soluble vitamins?
B,C
45
what is vitamin B1 and what can a lack of it cause?
thiamine causes Wernicke's encephalopathy
46
what is vitamin B6 and what can a lack of it cause?
pyroxidine causes peripheral neuropathy
47
what is vitamin B12 and what can a lack of it cause?
hydroxocobalamin/ cyanocobalamin causes megaloblastic anaemia
48
what is vitamin B2 and what can a lack of it cause?
riboflavin causes skin, eyes and nervous system problems
49
what can a lack of vitamin C cause?
scurvy (bleeding gums) impaired wound healing