blood & immune system lecture 4 Flashcards
what is the function of cytokines
aid in inflammatory & kill bacteria directly
what chemicals are involved in CRP?
interleukin 1 & 6 & TNF
do cytokines trigger clotting?
yes
what is the goal of cytokines?
tissue repair
how do cytokines repair tissue?
through cell division
what do interferons do?
reduce antiviral effects, limit viral spread
what is the complement system?
type of innate immunity, non-specific
what is the structure of dendritic cell
star shaped
what is the function of dendritic cell
tissue-resident cells that takes sips of fluid, chop up virus, take it to T cells to kill
what technique do dendritic cells use
macropinocytosis
what is macropinocytosis
taking tiny sips of fluid
where do immature dendritic cells reside
in peripheral tissue
how do dendritic cells migrate
via lymphatic vessel to regional lymph nodes
what does mature dendritic cells activate T cells
naive T cells in lymphoid organs like lymph nodes
when dendritic cells activate T cells, this is known as what kind of immunity
adaptive immunity
what are the 2 kinds of adaptive immunity
1) anti-body mediated or humoral immunity
2) cell-mediated immunity
are dendritic cells innate or adaptive
innate
what is anti-body mediated immunity
production of antibodies by B lymphocyte derivatives known as plasma cells
what is cell-mediated immunity
production of activated T lymphocytes to directly kill unwanted cells
what is specificity
lymphocytes recognizing different antigens
B lymphocytes
inactive lymphocytes
secrete antibodies
T lymphocytes
do not secrete antibodies
where are T cells made & mature
bone marrow & thymus
what are the 2 types of T cells
1) helper T cells
2) CD8 cells (cytotoxic & killer T cells)
what is the function of helper T cells?
activate macrophages & phagocytosis, make cytokines, activate B cells, becomes plasma cell
what is the function of CD8 cells?
destroy any foreign cells by binding to antigen which can kill cell directly or through use of enzyme
