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Hematology > Blood Group > Flashcards

Blood Group Flashcards

1
Q

The first to give IV infusions is

A

Boyle

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2
Q

Who discovered the ABO system

A

Karl Landsteiner in 1901

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3
Q

First anti-coagulant

A

Na citrate

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4
Q

First human blood transfusion

A

Agote in 1914

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5
Q

What can stimulate an immune response(antibody) in the body

A

Antigen

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6
Q

Antibodies are produced by

A

B lymphocytes

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7
Q

The ABO system is regulated by what chromosome

A

9

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8
Q

Blood grouping is based on

A

Red cell antigen

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9
Q

Blood group can be objectively determined at what age

A

> 2years

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10
Q

Silent gene or amorphs is for what blood group

A

O

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11
Q

Rhesus factors has what antigens

A

D antigen

d is an amorph

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12
Q

Almost all persons greater than 6/12 have what serums

A

Anti-A or Anti-B corresponding to which antigen is present or lacking

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13
Q

The human blood is grouped into how many ABO phenotypes

A

6 main

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14
Q

The ABO has how many antigens?

A

4 antigens

A1, A2, B, H

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15
Q

About 80% of the population have what antigen present in various body secretions.

A

A and B

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16
Q

O cells possess what antigen

A

Precursor H antigen

17
Q

H gene is present in all red cell groups except what type

A

Bombay red cells

18
Q

ABH antigens have what similar characteristics

A

Same 15 amino acids protein backbone

Same 4 sugar side-chain

19
Q

Specificity of the ABH antigen is determined by

A

Terminal sugars

20
Q

ABH antigens are also referred to as

A

Lewis substance

21
Q

The terminal sugars for
H antigen of group O?
Group A?
Group B?

A

L-fucose

L-fucose and galnac( N-acetyl galactosamine).

L-fucose and D-galactose

22
Q

Weak form of RhD antigen is

A

D^u

23
Q

How many genes controls rhesus

A

3 genes

24
Q

Causes of Hemolytic Disease of the Newborn include

A

Rhesus
Kell
Duffy
Kidd

Hematology (8 decks)

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