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Haemotology > Blood films > Flashcards

Blood films Flashcards

1
Q

when is a blood film carried out

A

Samples with significant results outside of the normal range, significant change within the normal and abnormal (either immature or unable to identify) cells highlighted by the analyser are identified

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2
Q

microcytic

A

parameter: mean cell volume (MCV)

meaning small RBC

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3
Q

macrocytic

A

parameter: mean cell volume (MCV)
meaning: large RBC

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4
Q

hypochromic

A

parameter: mean cell haemoglobin (MCH)
meaning: pale, less Hb

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5
Q

hyperchromic

A

parameter: mean cell haemoglobin (MCH)
meaning: dense, more Hb in given volume

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6
Q

anisocytosis

A

increased variability in size

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7
Q

dimorphisms

A

two distinct populations of red cells

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8
Q

poikilocytosis

A

abnormally shaped RBC

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9
Q

spherocytossi

A

spherical RBC

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10
Q

eliptocytosis

A

elliptical RBC

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11
Q

irregularly contracted cells

A

small dense RBC but not as regular in shape as spherocytes

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12
Q

echinocytes, acanthocytes, keratocytes, schistiocytes

A

spiculated cells

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13
Q

sickle cell

A

crescent or sickle shaped cells seen in sickle cell disease

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14
Q

taarget cells

A

RNC with dark area int he middle of the area of central pallor

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15
Q

normocytic

A

normal size

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16
Q

normochromic

A

normal color

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17
Q

macrocytic

A

abnormally large cells

18
Q

microcytic

A

abnormally small cells

19
Q

hyperchromic

A

densely packed Hb in the cell- appears darker than normal RBC

20
Q

hypochromic

A

less Hb in the cell- appears ligher and paler than ccells

21
Q

anisocytosis

A

variable sizes of RBC that is noticeably more than usual

22
Q

poikilocytosis

A

Variation in shape of RBC

23
Q

spherocytosis

A

RBC have a spehrical shape rather than a typical biconcave disck

24
Q

irregularly contracted cells

A

these are small dense RBC whose shape is not as regular as spherocytes, and have irregularly distributed condensed haemoglobin

25
Q

sickle cells

A

RBC are crescent (sickle) shaped

26
Q

tsarget cells (codocytes)

A

Hb is cocnentrated at the centre and the periphery of the RBC

27
Q

stomacytes

A

RBC have a pale slit in their centre, giving them a coffee bean appearance- lost biconcave shape so resemble a bowl

28
Q

schistocytes

A

RBC are fragmented

29
Q

acanthocytes

A

RBC have an irregular cell memrbane with a small number of spikey protrusions

30
Q

echinocytes (crenated cell)

A

RBC have an irregular cell membrane with a large number of regular spurs

  • like acanthocyte
31
Q

inclusions of erythrocytes

A

howell-jolly bodies

basophilic stippling

papenheimer bodies

heinz bodies

32
Q

howell-jolly bodes

A

DNA or nuclear fragments present in RBCs

33
Q

basophilic stipping

A

there are RNA inclusion in the RBC

34
Q

pappenheimer bodies

A

Iron inclusions in RBC (pearl stain)

35
Q

heinz bodies

A

there are clumps of denature Hb present in RBC

36
Q

Haemoglobin H inclusion ​

A

Gold ball cells; denatured haemoglobin H (brilliant cresyl blue stain)

37
Q

iron deficiency: FBC and red blood cell indices

A
  • Decreased:
    • Hb
    • MCV
    • MCG
    • MCHC
  • May occur in haemoglobinopathies
  • Increased RDW (more indicative of iron deficiency than thalassaemia
38
Q

iron deficiency: reticulocyte count

A

low or normal

  • reduced for the degree of anaemia
39
Q

iron deficiency: blood film

A
  • Hypochromic
  • Microcytic
  • Pencil cells
  • A few target cells
40
Q

vitamin B12 deficiency

A
  • Oval macrocytic
  • Basophilic stippling
  • Hyper segmental neutrophil
41
Q

platelets are very

A

reactive cells

  • If any clots in the sample the platelet count will be reduced
    • Try to citrate (green tube) sample to prevent platelet clumping

Haemotology (12 decks)

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