Blood coagulation Flashcards
1
Q
Aspirin
A
- prevent formation of throxane in platelets
- action of aspirin on platelet is permanent
2
Q
Heparin
A
- binds to thrombin (inactivates) and antithrombin III (activates)
- low mw heparins bind only to antithrombin III
3
Q
Warfarin
A
- blocks epoxide reductase in liver and prevents the regeneration of active form of Vit. K.
4
Q
Streptokinase
A
- thrombolytics agent
- plasminogen activator
- converts plasminogen to plasmin enabling the dissolution of clots
5
Q
Clopidogrel
A
- irreversibly inhibits P2Y12-R in platelets