Blood borne viruses Flashcards
how does Hep D infect
co - infects with Hep B , must have Hep B first
what groups are at greatest risk of blood borne virus infection
IV drug users
sexually active
healthcare workers (sharps injuries)
children from a disease-endemic birthplace
what makes a HBV infection chronic
HBsAG persists and no anti-Hbs after 6 months
is hep B dna or rna virus
DNA
what is the largest and only infectious particle of HBV
dane particle
is HCV a DNA or RNA virus
RNA
where in the body do both HCV and HBV replicate
liver
why is HIV so difficult to make a vaccine for
mutates each time it is transmitted and has developed resistance to anti virals
what are the 3 phases of HIV infection
primary infection
prolonged period of latency - no obvious symptoms , around 10 years usually
clinically apparent disease - severe symptoms
end point of disease = AIDS (more than 1 of indicator conditions of HIV present)