Blood Bank Flashcards

1
Q

HGB requirement for donors

A

12.5 g/dL (125 g/L)

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2
Q

Prior to donation collection, the venipuncture site must be cleaned with

A

PVP iodine complex

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3
Q

The Western blot is confirmatory for

A

anti-HIV-1

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4
Q

When aliquotting RBCs with a STERILE device, the expiration date will be

A

The same date as the original RBC unit

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5
Q

When platelets are stoed on a rotator set on an open benchtop, the ambiet air temperature must be recorded

A

every 4 hours

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6
Q

Platelets stored at 22-24C and gently agitated are good for

A

5 days

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7
Q

One thawed, fresh frozen plasma must be transfused within

A

24 hours

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8
Q

This may indicated contamination of platelets

A

Clots

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9
Q

a blood donor has the genotype:hh, AB. what is the red cell phenotype?

A

O. AB cannot be expressed due to hh

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10
Q

Fy(a-b-) is rare in all populations except

A

African Americans

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11
Q

The Xg blood group is encoded on the

A

X chromosome

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12
Q

To be a secreator, both the Lewis and the Se genes need to be present to type as

A

Le(a-b+)

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13
Q

Non-secreators will generally type as

A

Le(a+b-)

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14
Q

Ax cells are more strongly reactive with ________, than anti-A

A

anti-AB

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15
Q

A3 cells, when mixed with anti-A,B will show

A

mixed field agglutination

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16
Q

The enzyme responsible for confirring H activity on RBCs is

A

L-fucosyl transferase

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17
Q

Lutheran antiody best detected at lower temps

A

anti- Lu^a

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18
Q

Mixed-field refractile agglutinates are suggestive of

19
Q

HLA antibodies are induced by

A

multiple transfusions

20
Q

Genes of the MHC contributed to

A

the coordination of cellular and humoral immunity

21
Q

These red cell antigens are found on glycophorin-A

22
Q

Paraoxymal cold hemoglobinuria (PCH) is associated with antibody specificity toward

23
Q

This antibody is found in people with infectious mononucleosis

24
Q

Cold agglutinin syndrom is associated with an antibody specifity toward

25
At what temperatures does anti-I react best?
Room temp or 4 C
26
Resistance to malaria
Duffy
27
This is used to treat Hemophilia A
factor VIII concentrate
28
``` If an Rh mother has the following results D: 0 D cont:0 Weak D: 1+ (mf) Weak D cont: 0 what is the most likely cause? ```
Fetomaternal hemorrhage
29
When performing the rosette test, 1 rosette per 3 field is considered
negative (there was not an excessive bleed). The mother should receive i vial of RhIg for a normal bleed
30
Granulocytes for transfusion should be ABO compatible with
the patients plasma
31
When trasnfusing a neonate with group O cells, no crossmatch is necessary if
the initial plasma screening is negative
32
Babys usually will not express ABO antigens until
3 to 6 months of age
33
Forward: AB Reverse: A What is the cause of this ABO discrepancy?
Acquired B
34
In the cause of a group O individual with Tn polyagglutinable cells, they may appear to have
an acquired A antigen
35
The reagent used in weak D testing is
antiglobulin serum
36
On an antibody screen, if all screen cells AND the autocontrol are positive at IAT, the patient likely has a
warm autoantibody
37
If the Se and Le genes are both inherited, whats the phenotype?
Le(a-b+)
38
Aquired B occurs in individuals with this blood type. They will forward type _______ They will reverse type _______
A individuals Forward: AB Reverse: A
39
Forward: anti-A: 0 anti-B: 0 Reverse: A1: 0 B: 0 This patient is most likely
A baby under 3 months of age
40
The A3 subgroup can be suspected when cells show
mixed field agglutination
41
First Time 20yr old donor Forward: anti-A: 0 anti-B:0 Reverse: A: 0 B: 3+ This ABO discrepancy is most likely
A subgroup of A
42
RhIg Fetal Maternal Hemmorage | RhIg RBCs
Hemmorage: 30 mL RBCs: 15 mL
43
Patients with von Willibrand syndrome should be transfused with
cryparcipitate (includes vWB factors AND factor VIII) | vWF responsible for platelet aggregation due to ristocetin.
44
Unit of PLTs increase PLT count
5,000-10,000/mm