Blood and Renal

Question 1

Name 2 Gp IIb/III antagonists

Answer 1

Tirofiban, Eptifibatide, Abciximab

Question 2

Mechanism of action of aspirin as antiplatelet drug is it’s inhibitory action on

Answer 2

COX1

Question 3

Clopdogren is an antiplatelet agent that acts by

Answer 3

Irreversibly blocking P2Y12 receptors on the surface of platelet

Question 4

LMW heparin is preferred over unfractionated heparin because..

Answer 4

Less frequent thrombocytopenia, less haemorrhage complications

Question 5

Apixaban is a

Answer 5

Direct inhibitor of Xa

Question 6

Recent oral direct thrombin inhibitor used for stroke

Answer 6

Dabigatron

Question 7

What to do in Heparin induced Thrombocytopenia

Answer 7

Stop heparin, Lep Fonda Arg for 30 days

Question 8

Drug used in heparin OD

Answer 8

Protamine

Question 9

Orally acting direct thrombin inhibitor

Answer 9

Dabigatron

Question 10

The anticoagulant of choice in pregnancy

Answer 10

Heparin

Question 11

LMW heparin acts on

Answer 11

Xa only

Question 12

Thrombolytics can provide relative mortality reduction in the treatment of acute MI, if patient comes within..

Answer 12

7 - 12 hours

Question 13

Thiazides act on … region of the nephron

Answer 13

DCT

Question 14

Absolute CI for thrombolytics

Answer 14

Intracranial haemorrhage, Intracranial tumour

Question 15

Relative CI to thrombolytic therapy is

Answer 15

Uncontrolled Hypertension

Question 16

Furosemide acts on which region of nephron

Answer 16

PCT and DCT

Question 17

Name some Potassium sparring diuretics

Answer 17

Spironolactone, Amiloride, Triamterene

Question 18

Aldosterone antagonists are useful in the treatment of

Answer 18

CHF and Hypertension

Question 19

Aldosterone action is on which region

Answer 19

CD

Question 20

Thiazide diuretics ADR

Answer 20

Hypokalemia, Hyponatremia, Hypocalcemia, Hyperuricemia, acute saline depletion, Mg depletion, CNS disturbances

Question 21

Spironolactone is CI with enalapril because it causes

Answer 21

Hyperkalemia

Question 22

Loop diuretics such as furosemide act by

Answer 22

Inhibiting Na K 2Cl cotransport pump

Question 23

Treatment of choice of SIADH

Question 24

DOC for central diabetes insipidus

Answer 24

Desmopressin

Question 25

DOC for neurogenic diabetes insipidus

Answer 25

Desmopressin