Blood and Organs Flashcards

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1
Q

What are the four main components of the blood?

A

Plasma
Red blood cells
White blood cells
Platelets

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2
Q

What does plasma carry?

A
  1. Blood cells (white, red and platelets)
  2. Digested food products (e.g. glucose or amino acids)
  3. Carbon dioxide to the lungs
  4. Urea from the liver to the kidneys
  5. Hormones
  6. Heat energy
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3
Q

What are platelets?

A

Small fragments of cells that help blood clot

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4
Q

How do platelets allow the blood to clot?

A
  1. When a blood vessel is damaged, platelets clump together and ‘plug’ the damaged area
  2. They are held together by a mesh of protein called fibrin
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5
Q

How are red blood cells adapted for their job?

A
  1. Small with a biconcave shape to give a LSA
  2. Contain haemoglobin which carries the oxygen
  3. Don’t have a nucleus, freeing up space for more haemoglobin
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6
Q

What are the two main white blood cells?

A

Phagocytes
Lymphocytes

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7
Q

How do phagocytes deal with pathogens?

A
  1. Detect the foreign pathogens
  2. They engulf and digest them
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8
Q

How do lymphocytes deal with pathogens?

A
  1. Every pathogen have unique molecules (antigens) on their surface
  2. When a foreign antigen is encountered, lymphocytes produce antibodies
  3. These antibodies are specific to each antigen, and they lock onto the antigen and ‘mark them out’ for destruction from other WBC
  4. Antibodies are produced quickly and flow around the body to mark similar pathogens
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9
Q

What are memory cells?

A

Produced in response to a foreign antigen and remain in the body after the first encounter.

If the same antigen re-enters the body, the reproduce quickly to mark out that pathogen

Reason why the body is immune to disease you’ve already had

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10
Q

Why are vaccinations needed?

A

When infected with a pathogen, it can take a while to produce the antibodies. In this time, the person can get very ill and even die

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11
Q

How do vaccinations work?

A
  1. Inject a dead or inactive pathogen into the body. This will carry antigens from that pathogen
  2. These antigens will then trigger an immune response and antibodies are produced
  3. Memory cells are also produced and will remain in the blood. If live pathogens of the same type reappear, antibodies can be produced very quickly
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12
Q

What are the three types of blood vessels?

A

Arteries
Capillaries
Veins

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13
Q

What function do arteries provide?

A

Carry blood away from the heart

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14
Q

What function do capillaries provide?

A

Involved in the exchange of materials at the tissue

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15
Q

What function do veins provide?

A

Carry blood to the heart

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16
Q

How are arteries adapted for their job?

A
  1. Carry blood at high pressure, so the artery walls are strong and elastic
  2. The walls are thick compared to the size of the lumen
  3. The walls contain several layers of muscle
17
Q

How are capillaries adapted for their job?

A
  1. Thin, one cell thick walls, increasing rate of diffusion by decreasing distance
  2. Carry the blood really close to every cell in the body to exchange substances with them
  3. Permeable walls so substances can easily diffuse in and out
18
Q

How are veins adapted for their job?

A
  1. Blood is at a lower pressure so the walls are less thick
  2. Bigger lumen to help the blood flow despite low pressure
  3. Valves prevent blood flow in the wrong direction
19
Q

What is coronary heart disease?

A

A condition where the coronary arteries that supply the blood to the heart muscle gets blocked by layers of fatty material building up.

Blood flow is restricted and there’s a lack of oxygen to the heart muscle, leading to a heart attack

20
Q

What are risk factors that lead to coronary heart disease?

A
  1. A diet high in saturated fat
  2. Smoking increases blood pressure which can cause damage to the inside of the coronary arteries
  3. Chemicals in cigarettes make it more likely that fatty deposits will form
  4. Being inactive will lead to high blood pressure
21
Q

What are the three roles of the kidneys?

A
  1. Remove urea from the blood
  2. Adjustment of ion (salt) levels in the blood
  3. Adjustment of water content of the blood

Urea made in the liver from excess amino acids

22
Q

Where does ultrafiltration take place and what happens?

A

Glomerulus (bundle of capillaries at the start of the nephron -> Green part)

A high pressure build up squeezes water, urea, ions and glucose out of the blood into the Bowman’s capsule

Big molecules like proteins and blood cells are not squeezed out

23
Q

What molecules are squeezed into the Bowman’s capsule during ultrafiltration?

A

Water, urea, ions and glucose

24
Q

What process reabsorbs glucose back into the body and where does it take place?

A

Selective reabsorption

Proximal convoluted tubule (purple part)

All the glucose is reabsorbed from the proximal convoluted tubule so that it can be used for respiration (involves active transport)

25
Q

What process reabsorbs water back into the body and where does it take place?

A

Selective reabsorption

Collecting duct

Water is reabsorbed into the bloodstream by osmosis

26
Q

What happens with the filtrate left in the nephron (i.e. not selectively reabsorbed out)

A

The remaining substances (water, ions and urea) continues out of the nephron, through the ureter and into the bladder.

27
Q

How is water lost from the body?

A

Sweating
Urinating
Breathing

28
Q

What is osmoregulation?

A

The balance of water coming in and water going out, controlled by the body

29
Q

What is ADH?

ANTI Diuretic Hormone

Diruetic = Urine-related

A

Makes the collecting ducts of the nephron more permeable so more water is reabsorbed into the blood

30
Q

Explain the process of osmoregulation when a person is hydrated

A
  1. Hypothalamus detects high water levels in the blood
  2. Pituitary gland releases less ADH
  3. Collecting duct is less permeable so kidney will reabsorb less water
  4. The urine will have a larger volume and is more dilute
31
Q

Explain the process of osmoregulation when a person is dehydrated

A
  1. Hypothalamus detects low water levels in the blood
  2. Pituitary gland releases more ADH
  3. Collecting duct is more permeable so kidney will reabsorb more water
  4. The urine will have a smaller volume and is more concentrated