Blood Flashcards
Granular leukocytes
Grainy looking nucleus. Includes neutrophils, eosinopjils, and basophils.
Erythrocyte function
- Transport of respiratory gases when combined with hemoglobin
- Maintain acid base balance
Polycythemia
- RBC disorder characterized by increase in RBCs
- Usually caused by cancerous bone marrow
- Signs- increased blood thickness, slow blood flow, frequent hemorrhages, hypertension, distension of blood vessels.
- Treated by blood removal or chemotherapy or radiation to suppress bone marrow
Basophils
- Dark nucleus
- Are involved in inflammatory reactions and migrate to site of injury
- Contain histamine and anticoagulant heparin
Neutrophils
- Segmented nucleus, like beads
- Phagocytes that ingest and destroy invaders
- High with infections, low with B12 deficiency
Eosinophils
- Kidney shaped nucleus
- Attack objects that have already been coated with antibodies
- Phagocytes that will attack parasites, involved in allergic reactions
- High with infection or inflammation, low with bone marrow issues
Monocytes
- Much larger than other WBCs
- Aggressive phagocytes that attack larger microorganisms and cancer cells
- Release chemicals to attract neutrophils and other monocytes
- High with autoimmune and blood disorders, low with infections or bone marrow disorders
Lymphocytes
- Large nucleus with thin layer of cytoplasm
- B cells secrete antibodies
- T cells attack organisms
- NK cells- immune surveillance
- High with infections or leukemia, low with viral infections such as AIDs
- Receive signals from phagocytes
Clotting process
Rough blood vessel lining causes damaged tissues to release clotting factors. Platelets become sticky and plug the injury, prothrombin is converted to thrombin and reacts with fibrin to form a clot.
Clotting Disorders
- Hemophilia- genetic disease, lack of proteins to form blood clots.
- Thrombocytopenia- decrease in platelets causes bleeding
Anemia
- Not enough RBCs or deficient hemoglobin
- Iron deficiency, sickle cell, hemorrhagic- caused by trauma, aplastic- chemicals destroy bone marrow
- Symptoms- fatigue, pallor, faintness, headache, high heart and respiratory rates.
Plasma
Liquid part of blood containing water, dissolved food, waste, hormones and proteins.
Serum
Plasma without clotting agents.
Acidosis
Neutral blood (Ph should be 7.35-7.45)
Leukocytosis
Total WBC numbers over 10000 mm^3 of blood.
Frequently found in bacterial infections, and sign of leukemia.