Blood 4 Flashcards
What is the function of Prothrombin?
Converted into thrombin.
What type of molecule is Tissue thromboplastin or tissue factor?
Lipoprotein mixture.
What initiates the extrinsic pathway of coagulation?
Tissue thromboplastin or tissue factor.
What is the role of Calcium ions in the coagulation process?
Essential for the entire process.
What is the significance of Antihemophilic factor A?
Deficiency results in hemophilia A.
Where is Stuart–Prower factor produced?
Liver.
What does Antihemophilic factor C deficiency lead to?
Hemophilia C.
What is the function of Fibrin-stabilizing factor?
Stabilizes fibrin and slows fibrinolysis.
What initiates the extrinsic pathway of coagulation?
Damage to the surrounding tissue.
What do damaged extravascular cells release to start the extrinsic pathway?
Factor III (thromboplastin).
Which factor is activated by factor III to form an enzyme complex in the extrinsic pathway?
Factor VII (stable).
What does the enzyme complex formed in the extrinsic pathway activate?
Factor X (Stuart factor).
What initiates the intrinsic pathway of coagulation?
Factor XII (Hageman factor) coming in contact with foreign materials.
Which factor does factor XII activate in the intrinsic pathway?
Factor XI (Antihemophilic factor C).
What is the role of factor VIII in the intrinsic pathway?
It combines with factor IX to form an enzyme complex that activates factor X.
What is coagulation?
The process that leads to the formation of a blood clot.
What is a blood clot composed of?
A network of fibrin threads that trap blood cells, platelets, and fluid.
What activates factor X in the coagulation cascade?
The common pathway.
What does activated factor X convert prothrombin into?
Thrombin.
What is the role of thrombin in the coagulation cascade?
It converts fibrinogen into fibrin.
What stabilizes the fibrin clot?
Factor XIII (fibrin-stabilizing factor).
What is an antigen?
Any substance that causes your immune system to produce antibodies.
What are antibodies?
Proteins produced by the immune system in response to antigens.
What is the Rh group?
A classification of blood based on the presence or absence of the Rh antigen.
