Blood 4 Flashcards

1
Q

What is the function of Prothrombin?

A

Converted into thrombin.

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2
Q

What type of molecule is Tissue thromboplastin or tissue factor?

A

Lipoprotein mixture.

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3
Q

What initiates the extrinsic pathway of coagulation?

A

Tissue thromboplastin or tissue factor.

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4
Q

What is the role of Calcium ions in the coagulation process?

A

Essential for the entire process.

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5
Q

What is the significance of Antihemophilic factor A?

A

Deficiency results in hemophilia A.

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6
Q

Where is Stuart–Prower factor produced?

A

Liver.

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7
Q

What does Antihemophilic factor C deficiency lead to?

A

Hemophilia C.

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8
Q

What is the function of Fibrin-stabilizing factor?

A

Stabilizes fibrin and slows fibrinolysis.

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9
Q

What initiates the extrinsic pathway of coagulation?

A

Damage to the surrounding tissue.

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10
Q

What do damaged extravascular cells release to start the extrinsic pathway?

A

Factor III (thromboplastin).

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11
Q

Which factor is activated by factor III to form an enzyme complex in the extrinsic pathway?

A

Factor VII (stable).

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12
Q

What does the enzyme complex formed in the extrinsic pathway activate?

A

Factor X (Stuart factor).

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13
Q

What initiates the intrinsic pathway of coagulation?

A

Factor XII (Hageman factor) coming in contact with foreign materials.

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14
Q

Which factor does factor XII activate in the intrinsic pathway?

A

Factor XI (Antihemophilic factor C).

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15
Q

What is the role of factor VIII in the intrinsic pathway?

A

It combines with factor IX to form an enzyme complex that activates factor X.

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16
Q

What is coagulation?

A

The process that leads to the formation of a blood clot.

17
Q

What is a blood clot composed of?

A

A network of fibrin threads that trap blood cells, platelets, and fluid.

18
Q

What activates factor X in the coagulation cascade?

A

The common pathway.

19
Q

What does activated factor X convert prothrombin into?

A

Thrombin.

20
Q

What is the role of thrombin in the coagulation cascade?

A

It converts fibrinogen into fibrin.

21
Q

What stabilizes the fibrin clot?

A

Factor XIII (fibrin-stabilizing factor).

22
Q

What is an antigen?

A

Any substance that causes your immune system to produce antibodies.

23
Q

What are antibodies?

A

Proteins produced by the immune system in response to antigens.

24
Q

What is the Rh group?

A

A classification of blood based on the presence or absence of the Rh antigen.

25
Q

Which blood type is considered the universal donor?

A

O negative.

26
Q

Which blood type is considered the universal receiver?

A

AB.

27
Q

What agglutinogen does blood type A have?

A

A.

28
Q

What agglutinogen does blood type B have?

A

B.

29
Q

What agglutinogen does blood type AB have?

A

Both A & B.

30
Q

What agglutinogen does blood type O have?

A

Neither A & B.

31
Q

What is the compatible donor for blood type A?

A

A, O.

32
Q

What is the compatible donor for blood type B?

A

B, O.

33
Q

What is the compatible donor for blood type AB?

A

A, B, AB, O.

34
Q

What is the compatible donor for blood type O?

A

O.