BLOOD Flashcards
a transport system that transports nutrients, waste, and hormones
Blood
Erythrocytes sink to the bottom, 45% of blood, a percentage known as the
Hematocrit
Buffy coat is thick, whitish layer between the erythrocytes and plasma
White blood cells and platelets
rises to the top (55% of the blood)
Plasma
Color of oxygen-rich blood
Scarlet red
Color of oxygen-poor blood
Dull red or purple
The metallic and salty taste of blood is because of the presence of
Electrolytes
True or false. blood pH is slightly basic
False. Blood is slightly alkaline, between 7.35 and 7.45
How many liters of blood are found in a healthy adult?
5-6 liters
Blood makes up how much percent of body weight?
8%
The extracellular matrix of the blood; 90% water; Straw-colored fluid
Blood plasma
an important blood buffer and contributes to osmotic pressure
Albumin
clotting proteins; help to stem blood loss when a blood vessel is injured
Fibrinogen
help protect the body from pathogens
Globulin
3 formed elements from the blood
Erythrocytes, leukocytes, and thrombocytes
Main function is to carry oxygen that contains few organelles and lack mitochondria to make room for hemoglobin
Erythrocytes
True or false. Erythrocytes are shaped like biconcave discs
True
Normal count of RBCs
5 million per cubic mm
An erythrocyte can have ___ million hemoglobin molecule
250
is a decrease in the oxygen-carrying ability of the blood due to lower-than-normal number of RBCs and abnormal or deficient hemoglobin content in the RBCs
Anemia
results from abnormally shaped hemoglobin caused by the change of hemoglobin sequence of amino acids
Sickle cell anemia
is a disorder resulting from excessive or abnormal increase of RBCs
Polycythemia
Bone marrow cancer
Polycythemia Vera
Crucial in body’s defense against disease. Complete cells, with nucleus and organelles
Leukocytes
Leukocytes are able to move into and out of blood vessels through the process of
Diapedesis
Leukocytes’ response to chemical release by damaged tissues
Positive chemotaxis
Normal count of WBCs
4,800 to 10,800 per cubic mm
Leukocytes move by
Amoeboid motion
Granules in their cytoplasm can be stained that possess lobed nuclei. Includes neutrophils, eosinophils, and basophils
Granulocytes
Most numerous WBC, function as phagocytes at active sites of infection, and is stained pink
Neutrophils
Normal count of neutrophils
3,000 to 7,000 per cubic mm
Brick-red cytoplasmic granules that contains antihistamine to kill parasitic worms and play a role in allergy attacks
Eosinophils
Normal count of eosinophils
100-400 per cubic mm
Large histamine-containing granules that stain dark blue. Contains heparin (anticoagulant) - prevents the clotting mechanism from occurring
Basophils
Normal count of basophils
20-50 per cubic mm
Lack visible cytoplasmic granules with nuclei that are spherical, oval or kidney-shaped. Include lymphocytes and monocytes
Agranulocytes
has large dark purple nucleus and are slightly larger than RBCs. they reside in lymphatic tissues and play a role in immune response
Lymphocytes
Normal count of lymphocytes
1,500-3,000 per cubic mm
Largest of the white blood cells with a distinctive U or kidney shaped nucleus. They function as macrophages when they migrate into tissues, important in fighting chronic infection.
Monocytes
Normal count of monocytes
100-700 per cubic mm
Condition where WBC count above 11,000 cells per cubic mm of blood. Generally indicates an infection
Leukocytosis
Abnormally low WBC count. Commonly caused by certain drugs, such as corticosteroids ands anticancer agents
Leukopenia
Bone marrow becomes cancerous and numerous immature WBC are produced
Leukemia
Aka platelets, they are fragments of megakaryocytes (multinucleate cells) that are needed for the clotting process
Thrombocytes
Normal count of platelets
300,000 per cubic mm
Process of blood cell formation that occurs in red bone marrow
Hematopoiesis
Tissue in the bone marrow where blood cells are formed
Myeloid tissue
All blood cells are derived from a common stem cell called the
Hemocytoblast
produces lymphocytes
Lymphoid stem cells
produces all other formed elements other than lymphocytes
Myeloid stem cells
RBCs wear out after how many days?
100- 200 days
Worn out RBCs are eliminated by
Phagocytes
stimulates red bone marrow
Erythropoietin
Process of stopping the bleeding that results from a break in a blood vessel
Hemostasis
True or false. Blood usually clots within 8-10 minutes
False. Blood usually clots within 3-6 minutes
the enzyme that catalyzes joining of fibrinogen molecules in plasma to fibrin
Thrombin
forms a mesh that traps red blood cells and platelets, forming the clot
Fibrin
A clot in an unbroken blood vessel. Can be deadly in areas such as the lungs
Thrombus
A thrombus that breaks away and floats freely in the bloodstream that can later clog vessels in critical areas such as the brain
Embolus
Insufficient number of circulating platelets. Arises from any condition that suppresses the bone marrow
Thrombocytopenia
Hereditary bleeding disorder where normal clotting factors are missing. Minor tissue damage can cause life-threatening prolonged bleeding
Hemophilia