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Step 1 Pharmacology > α-blockers > Flashcards

α-blockers Flashcards

1
Q

Nonselective - What are the applications of Phenoxybenzamine (irreversible)?

A

Pheochromocytoma (used preoperatively) to prevent catecholamine (hypertensive) crisis

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2
Q

Nonselective - What toxicity does Phenoxybanzamine (irreversible) have?

A

Orthostatic hypotension; reflex tachycardia

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3
Q

Nonselective - What are the applications of Phentolamine (reversible)?

A

Give to patients on MAO inhibitors who eat tyramine-containing foods

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4
Q

α1 selective (-osin) - What are the applications of Prazosin, Terazosin, Doxazosin, Tamsulosin?

A

Urinary symptoms of BPH; PTSD (prazosin); hypertension (except tamsulosin)

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5
Q

α1 selective (-osin) - What toxicites do Prazosin, Terazosin, Doxazosin, Tamsulosin have?

A

1st-dose orthostatic hypotension, dizziness, and headache

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6
Q

α2 selective - What is the application of Mirtazapine?

A

Depression

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7
Q

α2 selective - What toxicities do Mirtazapine have?

A

Sedation, ↑ serum cholesterol, ↑ appetite

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Step 1 Pharmacology (18 decks)

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